Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123641 | 0.84 | NOTUM (0.35) | ALDH1A1L3MBTL1NOTUM | |
| SCHEMBL20123632 | 0.82 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL20123727 | 0.80 | ACHE (0.35) | MEN1KMT2ANOTUM | |
| SCHEMBL20123824 | 0.77 | MEN1 (0.34) | MEN1KMT2A | |
| SCHEMBL20123771 | 0.77 | TEAD1 (0.33) | ALDH1A1L3MBTL1HTR2AHTR2CHRH1 | |
| SCHEMBL21183807 | 0.77 | CXCR5 (0.33) | MEN1KMT2A | |
| SCHEMBL20014747 | 0.74 | KMT2A (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20123649 | 0.74 | ACHE (0.35) | MEN1KMT2ANOTUM | |
| SCHEMBL20123600 | 0.71 | ADRA2A (0.33) | MEN1KMT2A | |
| SCHEMBL28259616 | 0.70 | CHRNB2 (0.40) | ALDH1A1L3MBTL1HTR2AHTR2CHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |