Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20123824 | 0.86 | MEN1 (0.34) | MEN1KMT2ANPC1LMNATP53 | |
| SCHEMBL20123727 | 0.86 | ACHE (0.35) | MEN1KMT2ANPC1LMNATP53 | |
| SCHEMBL20123649 | 0.86 | ACHE (0.35) | MEN1KMT2ANPC1LMNATP53 | |
| SCHEMBL20123600 | 0.86 | ADRA2A (0.33) | MEN1KMT2ANPC1LMNATP53 | |
| SCHEMBL20014747 | 0.83 | KMT2A (0.41) | MEN1KMT2ANPC1LMNATP53 | |
| SCHEMBL20123682 | 0.82 | ALDH1A1 (0.37) | MEN1KMT2A | |
| SCHEMBL21183807 | 0.82 | CXCR5 (0.33) | MEN1KMT2A | |
| SCHEMBL20014517 | 0.80 | MEN1 (0.43) | MEN1KMT2ANPC1LMNATP53 | |
| SCHEMBL6904839 | 0.73 | PARP1 (0.38) | SMN1; SMN2CA1CA2CA7CA9 | |
| SCHEMBL1192279 | 0.71 | DRD2 (0.41) | MEN1KMT2ASMN1; SMN2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2620436-B1 | SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG | SHIONOGI & CO (JP) | 2018-05-09 | — | — | EP | disclosed |