Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038718 | 0.74 | LMNA (0.33) | POLBTP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2012604 | 0.71 | FKBP1A (0.32) | HTTPOLBTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2016596 | 0.71 | SMN1; SMN2 (0.33) | POLBTP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2015146 | 0.69 | MAPT (0.48) | HPGDTP53ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2013111 | 0.61 | KDM4E (0.35) | POLBALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL10112658 | 0.60 | SLC6A2 (0.41) | HPGDALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL22499881 | 0.60 | EPHX2 (0.41) | HTTHPGDALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL5442325 | 0.60 | KIF11 (0.38) | HTTPOLBALDH1A1SMN1; SMN2KIF11 | |
| SCHEMBL22499927 | 0.58 | EPHX2 (0.40) | HTTALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL11213786 | 0.57 | KIF11 (0.48) | HTTALDH1A1SMN1; SMN2MAPTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513069-A1 | ANTIFUNGAL COMPOUNDS | Katholieke Universiteit Leuven (BE) | 2012-10-24 | — | — | EP | disclosed |
| WO-2011072345-A1 | ANTIFUNGAL COMPOUNDS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2011-06-23 | — | — | WO | disclosed |