SCHEMBL201397

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5800279	0.85	CES2 (0.39)	PBRM1CES2CES1PARP1
	SCHEMBL27759044	0.82	CA1 (0.44)	HSD17B1HSD17B2CYP3A4MAPK1CES2
	SCHEMBL4042914	0.82	PBRM1 (0.40)	PBRM1CES2CES1PARP1
	SCHEMBL5173385	0.79	CYP3A4 (0.50)	WEE1PKMYT1CYP3A4MAPK1PBRM1
	SCHEMBL201485	0.79	HSD17B1 (0.44)	HSD17B1HSD17B2CYP3A4CES2CES1
	SCHEMBL4026715	0.78	POLB (0.42)	CYP3A4MAPK1PBRM1CES2CES1
	SCHEMBL14661433	0.78	DGAT1 (0.39)	PBRM1CES2CES1PARP1
	SCHEMBL6818860	0.75	PBRM1 (0.41)	PBRM1CES2CES1PARP1
	SCHEMBL17188008	0.74	CYP11B2 (0.40)	ESR1ESR2
	SCHEMBL202632	0.74	POLB (0.46)	HSD17B1HSD17B2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.