SCHEMBL201485

SCHEMBL201485

NC(=O)c1c(F)ccc(O)c1F

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 18/20 0.44
HSD17B2 P37059 18/20 0.44
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2B6 P20813 1/20 0.38
CYP2C19 P33261 1/20 0.38
STS P08842 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7146004 0.84 CES2 (0.46) CES2CES1
SCHEMBL29782972 0.84 CES2 (0.46) CES2CES1
SCHEMBL27433691 0.80 HSD17B1 (0.49) HSD17B1HSD17B2CYP3A4CYP2D6CYP2C9
SCHEMBL31197230 0.80 HSD17B1 (0.49) HSD17B1HSD17B2CYP3A4CYP2D6CYP2C9
SCHEMBL201397 0.79 HSD17B1 (0.41) HSD17B1HSD17B2CYP3A4STSCES2
SCHEMBL202186 0.79 HSD17B1 (0.46) HSD17B1HSD17B2CYP3A4
SCHEMBL24445882 0.78 THRB (0.46) HSD17B1HSD17B2CYP3A4
SCHEMBL17275022 0.78 CES2 (0.38) CYP3A4CYP2C9CYP2C19CES2CES1
SCHEMBL6818860 0.78 PBRM1 (0.41) CES2CES1
SCHEMBL30739599 0.78 CES2 (0.38) CYP3A4CYP2C9CYP2C19CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111848540-A Chain transfer agent for preparing antibacterial polymer and preparation method thereof 吴张峰 2020-10-30 CN claimed
CN-111728837-A Exercise massage belt capable of rubbing abdomen and chest and throwing butterfly sleeves and preparation method thereof 万贤能 2020-10-02 CN claimed
US-20250257074-A1 SYNTHETIC PROCESSES AND SYNTHETIC INTERMEDIATES TAXIS PHARMACEUTICALS, INC. (US) 2025-08-14 US disclosed
US-20250206755-A1 ANTIMICROBIAL AGENTS RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2025-06-26 US disclosed
US-20250179008-A1 ANTIBACTERIAL AGENTS TAXIS PHARMACEUTICALS, INC. (US) 2025-06-05 US disclosed
US-12173013-B2 Synthetic processes and synthetic intermediates TAXIS PHARMACEUTICALS, INC. (US) 2024-12-24 US disclosed
US-12061201-B2 Fluorescent probes for the visualization of FtsZ in gram-positive and gram-negative bacterial pathogens RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) 2024-08-13 US disclosed
CN-110891566-B Synthesis method and synthesis intermediate 塔克西斯医药股份有限公司 2023-12-19 CN disclosed
US-20230257397-A1 SYNTHETIC PROCESSES AND SYNTHETIC INTERMEDIATES TAXIS PHARMACEUTICALS, INC. (US) 2023-08-17 US disclosed
US-20230257397-A1 SYNTHETIC PROCESSES AND SYNTHETIC INTERMEDIATES TAXIS PHARMACEUTICALS, INC. (US) 2023-08-17 US disclosed
US-20230257397-A1 SYNTHETIC PROCESSES AND SYNTHETIC INTERMEDIATES TAXIS PHARMACEUTICALS, INC. (US) 2023-08-17 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
US-20100173933-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2010-07-08 US disclosed
EP-2203219-A1 SUBSTITUTED BENAMIDINES AS ANTIBACTERIAL AGENTS Biota Europe Ltd (GB) 2010-07-07 EP disclosed
EP-2200991-A1 ANTIBACTERIAL AGENTS Biota Europe Ltd (GB) 2010-06-30 EP disclosed
WO-2009040507-A1 SUBSTITUTED BENAMIDINES AS ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2009-04-02 WO disclosed
WO-2009037485-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2009-03-26 WO disclosed
EP-1996180-A1 ANTIBACTERIAL AGENTS Prolysis Limited (GB) 2008-12-03 EP disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed
WO-2007107758-A1 ANTIBACTERIAL AGENTS PROLYSIS LTD (GB) 2007-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230257397-A1 SYNTHETIC PROCESSES AND SYNTHETIC INTERMEDIATES TXN, TBXAS1, TXK HSD17B1 3460/4885HSD17B2 3824/4885CYP3A4 367/4885
US-12061201-B2 Fluorescent probes for the visualization of FtsZ in gram-positive and gram-negative bacterial pathogens CDC42, DNM1L, IK HSD17B1 3180/4885HSD17B2 3655/4885CYP3A4 4764/4885
US-20250257074-A1 SYNTHETIC PROCESSES AND SYNTHETIC INTERMEDIATES TXN, TBXAS1, TXK HSD17B1 3460/4885HSD17B2 3824/4885CYP3A4 367/4885
US-20250206755-A1 ANTIMICROBIAL AGENTS CFTR, MRPL21, ARG1 HSD17B1 3123/4885HSD17B2 3540/4885CYP3A4 1709/4885
US-20250179008-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 HSD17B1 2303/4885HSD17B2 2276/4885CYP3A4 795/4885
US-20100173933-A1 ANTIBACTERIAL AGENTS ALK, ROS1, NOX1 HSD17B1 2303/4885HSD17B2 2276/4885CYP3A4 795/4885
US-12173013-B2 Synthetic processes and synthetic intermediates TXN, TBXAS1, TXK HSD17B1 3460/4885HSD17B2 3824/4885CYP3A4 367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.