Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMO | Q99835 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20139858 | 0.83 | PKM (0.47) | PKMPPARGPOLBSMN1; SMN2GAA | |
| SCHEMBL20141007 | 0.82 | PKM (0.48) | PKMPPARGPOLBMEN1KMT2A | |
| SCHEMBL20139969 | 0.80 | MTOR (0.49) | SMN1; SMN2GAATSHRTNFRAB9A | |
| SCHEMBL11180220 | 0.71 | PKM (0.61) | PKMKMT2ASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL20141002 | 0.71 | MCL1 (0.46) | PKMPOLBKMT2ASMN1; SMN2GAA | |
| SCHEMBL20141897 | 0.71 | HTT (0.47) | PKMPPARGPOLBGAATSHR | |
| SCHEMBL20140581 | 0.69 | KDM4E (0.52) | PPARGMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL1295729 | 0.69 | DGAT1 (0.47) | PPARGGPR119 | |
| SCHEMBL20141494 | 0.68 | HRH3 (0.53) | PKMPPARGSMN1; SMN2KDM4ELMNA | |
| SCHEMBL14087184 | 0.68 | HDAC3 (0.49) | PKMMEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |