Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 1/20 | 0.38 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | PLK4 | O00444 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | LTK | P29376 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | PRKX | P51817 | 1/20 | 0.37 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.37 |
| ▸ | MST1R | Q04912 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20141654 | 0.72 | HDAC1 (0.47) | MAP4K4HTR1A | |
| SCHEMBL20141652 | 0.72 | HDAC1 (0.47) | MAP4K4HTR1A | |
| SCHEMBL20141470 | 0.71 | SLC16A3 (0.32) | SLC16A3SLC16A1 | |
| SCHEMBL20141435 | 0.65 | HTR1A (0.44) | ROCK1NOS1HTR1ACYP3A4 | |
| SCHEMBL20141437 | 0.65 | HTR1A (0.44) | ROCK1NOS1HTR1ACYP3A4 | |
| SCHEMBL28809309 | 0.65 | ALDH1A1 (0.45) | HCRTR1HCRTR2KDM4EMAPTTHRB | |
| SCHEMBL22337746 | 0.63 | PIK3CD (0.41) | CDK5PLK4CHEK1AURKADAPK3 | |
| SCHEMBL17738375 | 0.63 | ALDH1A1 (0.56) | CDK5PLK4CHEK1AURKADAPK3 | |
| SCHEMBL20142570 | 0.62 | KEAP1 (0.38) | HCRTR1HCRTR2 | |
| SCHEMBL4558300 | 0.61 | SLC6A9 (0.44) | HTR1AKDM4ECYP1A2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |