Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 1/20 | 0.43 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | ATR | Q13535 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17339936 | 0.85 | FPR2 (0.57) | FPR2PROKR1POLBMMP1HTR2C | |
| SCHEMBL21652006 | 0.85 | FPR2 (0.47) | FPR2PROKR1MMP1HTR2CHTR2B | |
| SCHEMBL1926965 | 0.83 | IL1B (0.43) | IL1BNLRP3CHRM2CHRM1CHRM3 | |
| SCHEMBL20145024 | 0.83 | TDO2 (0.48) | IL1BNLRP3CHRM2CHRM1CHRM3 | |
| SCHEMBL20145042 | 0.81 | PDE3B (0.47) | L3MBTL1POLBCHRM2CHRM1CHRM3 | |
| SCHEMBL20145092 | 0.81 | FPR2 (0.43) | L3MBTL1FPR2PROKR1MMP1 | |
| SCHEMBL4051291 | 0.80 | FPR2 (0.47) | L3MBTL1FPR2PROKR1MMP1 | |
| SCHEMBL20145221 | 0.80 | IL1B (0.55) | IL1BNLRP3 | |
| SCHEMBL20144750 | 0.80 | IL1B (0.55) | IL1BNLRP3 | |
| SCHEMBL5274039 | 0.79 | MMP1 (0.44) | FPR2PROKR1MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970207-B1 | SUBSTITUTED PIPERIDINE COMPOUNDS AND THEIR USE AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2018-05-16 | — | — | EP | disclosed |