Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20148198 | 0.83 | HDAC3 (0.44) | HRH3PARP1AOC3NPC1RAB9A | |
| SCHEMBL20148201 | 0.82 | HRH3 (0.47) | HRH3PARP1AOC3 | |
| SCHEMBL20148196 | 0.81 | HRH3 (0.58) | OPRM1OPRK1HRH3PARP1KDM1A | |
| SCHEMBL2828056 | 0.80 | OPRM1 (0.60) | OPRM1OPRK1HRH3SMOPARP1 | |
| SCHEMBL4460927 | 0.78 | RAB9A (0.56) | OPRM1OPRK1HRH3SMOPARP1 | |
| SCHEMBL30754039 | 0.78 | HRH3 (0.56) | OPRM1OPRK1HRH3SMOPARP1 | |
| Hydrochloric Acid SCHEMBL5009801 | 0.77 | RAB9A (0.55) | OPRM1OPRK1HRH3SMOPARP1 | |
| SCHEMBL30753988 | 0.76 | HRH3 (0.70) | OPRM1OPRK1HRH3SMOPARP1 | |
| SCHEMBL29475033 | 0.76 | UBE2T (0.71) | OPRM1OPRK1HRH3SMOPARP1 | |
| SCHEMBL30289763 | 0.76 | UBE2T (0.71) | OPRM1OPRK1HRH3SMOPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180134688-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180134688-A1 | NOVEL COMPOUNDS | RIPK2, RIPK1, RIPK4 | OPRM1 4521/4885OPRK1 3162/4885HRH3 3405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.