Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 8/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.40 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20140902 | 0.80 | HTR7 (0.48) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL20141745 | 0.79 | DRD4 (0.49) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL20139967 | 0.78 | NAMPT (0.48) | TRPC5KDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL20156931 | 0.77 | MTOR (0.51) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL20140648 | 0.76 | PRMT5 (0.42) | TRPC5KDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL20140096 | 0.76 | PARP1 (0.45) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL20140759 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL20140640 | 0.76 | KDM4E (0.56) | KDM4EALDH1A1PLA2G1BRAB9AATG4B | |
| SCHEMBL20141481 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1DRD2DRD4DRD3 | |
| SCHEMBL20140667 | 0.74 | TRPC5 (0.42) | TRPC5KDM4EALDH1A1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018089433-A1 | PHENYL mTORC INHIBITORS AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2018-05-17 | — | — | WO | disclosed |