SCHEMBL20157560

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20157898	0.88	PTPN1 (0.43)	PTPN1CES2CES1S1PR1LTA4H
	SCHEMBL20157516	0.86	ALDH1A1 (0.48)	CES2CES1LMNASMN1; SMN2HTT
	SCHEMBL20157523	0.85	CES2 (0.39)	PTPN1CES2CES1S1PR1LTA4H
	SCHEMBL20157960	0.84	SRD5A2 (0.49)	CES2CES1LMNAHTTSRD5A2
	SCHEMBL20157297	0.84	GSK3B (0.43)	CES2CES1SRD5A2MAPK1MAPT
	SCHEMBL11860220	0.83	LTA4H (0.46)	PTPN1CES2CES1LTA4HLMNA
	SCHEMBL20157777	0.83	CES2 (0.47)	CES2CES1HTTKMT2A
	SCHEMBL20157757	0.82	LMNA (0.50)	PTPN1CES2CES1S1PR1LMNA
	SCHEMBL21351905	0.81	CA2 (0.41)	S1PR1LMNASMN1; SMN2HTTNPC1
	SCHEMBL20157557	0.81	PTPN1 (0.39)	PTPN1CES2CES1S1PR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.