SCHEMBL2015762

SCHEMBL2015762

Fc1cc(F)cc(-c2ccc[c]c2C(F)(F)F)c1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.35
HTR7 P34969 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2430766 0.86 NT5E (0.41) HTR1AHTR7
SCHEMBL2431522 0.84 ENPP1 (0.39) HTR1AHTR7
SCHEMBL455371 0.79 ALDH1A1 (0.40)
SCHEMBL2428521 0.79 HSD17B1 (0.34)
SCHEMBL15663248 0.76 KIF11 (0.45)
SCHEMBL1207131 0.76 RORC (0.43) HTR1AHTR7
SCHEMBL2053315 0.76 PDK2 (0.35)
SCHEMBL2050765 0.76 PTPN1 (0.36)
SCHEMBL2013153 0.76 HTR1A (0.35) HTR1AHTR7
SCHEMBL3678971 0.75 ENPP1 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011113820-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2011-09-22 WO disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed