Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19911192 | 0.92 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL19915462 | 0.84 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL20194263 | 0.83 | ALDH1A1 (0.33) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL19911208 | 0.81 | ZDHHC20 (0.32) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL20061003 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| Succinic Acid SCHEMBL28603395 | 0.79 | TSHR (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL14864702 | 0.79 | LMNA (0.44) | ALDH1A1TSHRMAPK1TDP1 | |
| SCHEMBL20159780 | 0.78 | ZDHHC20 (0.46) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL15270995 | 0.74 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 | |
| SCHEMBL20194268 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3981433-A1 | COVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME | RemeGen Biosciences, Inc. (US) | 2022-04-13 | — | — | EP | disclosed |
| EP-3334462-B1 | COVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME | RC BIOTECHNOLOGIES INC (US) | 2022-01-19 | — | — | EP | disclosed |
| US-10772965-B2 | Covalent linkers in antibody-drug conjugates and methods of making and using the same | RC BIOTECHNOLOGIES, INC. (US) | 2020-09-15 | — | — | US | disclosed |
| US-20180169250-A1 | COVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME | REMEGEN CO., LTD. (CN) | 2018-06-21 | — | — | US | disclosed |
| US-20180055948-A1 | Covalent Linkers in Antibody-Drug Conjugates and Methods of Making and Using the Same | REMEGEN CO., LTD. (CN) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180169250-A1 | COVALENT LINKERS IN ANTIBODY-DRUG CONJUGATES AND METHODS OF MAKING AND USING THE SAME | DHFR, FCGR1A, ADCY4 | ALDH1A1 211/4885TSHR 624/4885MAPK1 2345/4885 |
| US-20180055948-A1 | Covalent Linkers in Antibody-Drug Conjugates and Methods of Making and Using the Same | DHFR, FCGR1A, ADCY4 | ALDH1A1 211/4885TSHR 624/4885MAPK1 2345/4885 |
| US-10772965-B2 | Covalent linkers in antibody-drug conjugates and methods of making and using the same | DHFR, FCGR1A, ADCY4 | ALDH1A1 211/4885TSHR 624/4885MAPK1 2345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.