SCHEMBL20160481

SCHEMBL20160481

IN1c2ccccc2C(c2ccccc2)(c2ccccc2)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.38
GAA P10253 2/20 0.38
MCL1 Q07820 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PAX8 Q06710 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
P2RX1 P51575 1/20 0.37
P2RX3 P56373 1/20 0.37
P2RX4 Q99571 1/20 0.37
P2RX7 Q99572 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 2/20 0.36
OPRK1 P41145 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CNR1 P21554 1/20 0.36
GPR55 Q9Y2T6 1/20 0.36
ADRB2 P07550 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25472299 0.79 ALDH1A1 (0.32) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL21387931 0.78 LMNA (0.41) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL21184892 0.78 MEN1 (0.41) LMNAMEN1KMT2AMAPTKDM4E
SCHEMBL18387330 0.78 P2RX1 (0.41) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL280034 0.78 LMNA (0.47) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL30585081 0.78 LMNA (0.47) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL2754763 0.77 ALDH1A1 (0.41) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL13231436 0.77 ALDH1A1 (0.37) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL20383139 0.77 P2RX1 (0.47) LMNAGAAMCL1ALDH1A1PAX8
SCHEMBL29833177 0.77 ALDH1A1 (0.41) LMNAGAAMCL1ALDH1A1PAX8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230157163-A1 ORGANIC COMPOUND, PREPARATION METHOD THEREOF, AND DISPLAY PANEL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-18 US disclosed
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2023-05-04 US disclosed
US-10673000-B2 Heterocyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-06-02 US disclosed
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230157163-A1 ORGANIC COMPOUND, PREPARATION METHOD THEREOF, AND DISPLAY PANEL HTR4, AR, HTR2C LMNA 4298/4885GAA 4265/4885MCL1 2521/4885
US-20180138429-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME ODC1, KCNC1, KCNH1 LMNA 2960/4885GAA 2418/4885MCL1 984/4885
US-20230137446-A1 THERMALLY ACTIVATED DELAYED FLUORESCENT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE DNTT, CD69, DUT LMNA 820/4885GAA 926/4885MCL1 2884/4885
US-10673000-B2 Heterocyclic compound and organic electroluminescence device including the same ODC1, KCNC1, KCNH1 LMNA 2960/4885GAA 2418/4885MCL1 984/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.