SCHEMBL2754763

SCHEMBL2754763

c1ccc(N2c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
THPO P40225 1/20 0.41
MAPK1 P28482 1/20 0.39
LMNA P02545 3/20 0.37
GAA P10253 3/20 0.37
CES2 O00748 1/20 0.37
BCHE P06276 1/20 0.37
CES1 P23141 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
EGLN1 Q9GZT9 2/20 0.37
ADAMTS5 Q9UNA0 1/20 0.37
PAX8 Q06710 1/20 0.36
MCL1 Q07820 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29833177 1.00 ALDH1A1 (0.41) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL20383358 0.96 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15030649 0.96 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13231436 0.96 ALDH1A1 (0.37) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL12723310 0.93 ALDH1A1 (0.37) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL20383365 0.91 ALDH1A1 (0.36) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL20383356 0.91 FAAH (0.38) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL14398805 0.90 FAAH (0.40) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL13143179 0.90 FAAH (0.35) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15385881 0.89 CNR1 (0.42) ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11725003-B2 Amine derivative and an organic electroluminescent device thereof CHANGCHUN HYPERIONS TECHNOLOGY CO., LTD (CN) 2023-08-15 US disclosed
US-11725003-B2 Amine derivative and an organic electroluminescent device thereof CHANGCHUN HYPERIONS TECHNOLOGY CO., LTD (CN) 2023-08-15 US disclosed
CN-115093437-A Boron-nitrogen heterocyclic derivative based on fusion donor, preparation and application thereof 华中科技大学 2022-09-23 CN disclosed
US-11183643-B2 Nitrogen heterocycle fused ring-indene compound and organic light-emitting display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2021-11-23 US disclosed
US-20210009574-A1 Amine derivative and an organic electroluminescent device thereof CHANGCHUN HYPERIONS TECHNOLOGY CO., LTD (CN) 2021-01-14 US disclosed
US-10833280-B2 Condensed cyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-11-10 US disclosed
US-20200035929-A1 NITROGEN HETEROCYCLE FUSED RING-INDENE COMPOUND AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE Shanghai Tianma AM-OLED Co., Ltd. (CN) 2020-01-30 US disclosed
US-20190252624-A1 ORGANIC SEMICONDUCTOR COMPOSITION AND SEMICONDUCTING LAYER OBTAINED THEREFROM SOLVAY SA (BE) 2019-08-15 US disclosed
US-20180269404-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-09-20 US disclosed
EP-3258509-A1 9,9-DISUBSTITUTED 9,10-DIHYDROACRIDINE COMPOUNDS AND THEIR USE FOR DOPING CRYSTALLINE ORGANIC SEMICONDUCTORS Solvay SA (BE) 2017-12-20 EP disclosed
US-20120001537-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-01-05 US disclosed
US-20120001537-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-01-05 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
US-20100219406-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR ELECTRON BLOCKERS IN OLEDS BASF SE (DE) 2010-09-02 US disclosed
EP-2195868-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS Basf Se (DE) 2010-06-16 EP disclosed
US-20100019658-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-01-28 US disclosed
US-20100019658-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-01-28 US disclosed
WO-2009047147-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS BASF SE (DE) 2009-04-16 WO disclosed
WO-2009047147-A1 USE OF ACRIDINE DERIVATIVES AS MATRIX MATERIALS AND/OR AN ELECTRON BLOCKER IN OLEDS BASF SE (DE) 2009-04-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200035929-A1 NITROGEN HETEROCYCLE FUSED RING-INDENE COMPOUND AND ORGANIC LIGHT-EMITTING DISPLAY DEVICE C1S, CRY2, CRY1 ALDH1A1 982/4885CYP1A2 310/4885CYP3A4 1260/4885
US-20210009574-A1 Amine derivative and an organic electroluminescent device thereof AOC1, AOX1, AOC2 ALDH1A1 22/4885CYP1A2 1603/4885CYP3A4 1784/4885
US-11183643-B2 Nitrogen heterocycle fused ring-indene compound and organic light-emitting display device C1S, CRY2, CRY1 ALDH1A1 982/4885CYP1A2 310/4885CYP3A4 1260/4885
US-11725003-B2 Amine derivative and an organic electroluminescent device thereof AOC1, AOX1, AOC2 ALDH1A1 22/4885CYP1A2 1603/4885CYP3A4 1784/4885
US-20120001537-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME OR10J3, ORC3, PIEZO1 ALDH1A1 738/4885CYP1A2 2391/4885CYP3A4 1321/4885
US-20100019658-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE EMPLOYING THE SAME OR10J3, DDT, HRH4 ALDH1A1 2491/4885CYP1A2 1548/4885CYP3A4 992/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.