SCHEMBL20172864

SCHEMBL20172864

CN(c1ccccc1OC(F)(F)F)c1cccc2c1oc1c([Si](C)(C)C)cccc12

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.33
C1R P00736 1/20 0.33
RPS6KA2 Q15349 1/20 0.32
L3MBTL1 Q9Y468 2/20 0.31
ACP1 P24666 1/20 0.31
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
ALDH1A1 P00352 1/20 0.31
SCN9A Q15858 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20172808 0.85 L3MBTL1 (0.32) EPHX2C1RRPS6KA2L3MBTL1ACP1
SCHEMBL20172815 0.85 S1PR1 (0.33) EPHX2C1RRPS6KA2L3MBTL1ACP1
SCHEMBL21020291 0.85
SCHEMBL20172843 0.84 HSD11B1 (0.36) EPHX2C1RRPS6KA2L3MBTL1ACP1
SCHEMBL20172792 0.84 MAOA (0.39) EPHX2C1RRPS6KA2L3MBTL1KDM4E
SCHEMBL20172834 0.83 HTR6 (0.32) EPHX2C1RRPS6KA2L3MBTL1ALDH1A1
SCHEMBL21020270 0.82 KCNK3 (0.39) EPHX2C1RRPS6KA2L3MBTL1ALDH1A1
SCHEMBL21021485 0.82 ACP1 (0.37) EPHX2ACP1
SCHEMBL21020437 0.82 SLC6A3 (0.36) C1RL3MBTL1KDM4EALDH1A1
SCHEMBL20172860 0.81 C1R (0.31) C1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10651411-B2 Compound and organic light emitting device containing same LG CHEM, LTD. (KR) 2020-05-12 US disclosed
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEM, LTD. (KR) 2019-05-23 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME LG CHEM, LTD. (KR) 2018-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180145272-A1 COMPOUND AND ORGANIC LIGHT EMITTING DEVICE CONTAINING SAME CRY1, CRY2, OR10J3 EPHX2 247/4885C1R 3637/4885RPS6KA2 4588/4885
US-20190152919-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME OR10J3, ETV6, ESR1 EPHX2 150/4885C1R 4162/4885RPS6KA2 3743/4885
US-10651411-B2 Compound and organic light emitting device containing same CRY1, CRY2, OR10J3 EPHX2 247/4885C1R 3637/4885RPS6KA2 4588/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.