SCHEMBL2017384

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2018298	0.90	BRD4 (0.48)	HTR6BRD4BRD1BRPF1HTR2C
	SCHEMBL2015259	0.88	HTR6 (0.45)	HTR6BRD4HTR2CHTR2AHTR2B
	SCHEMBL692281	0.88	HTR6 (0.49)	HTR6HTR2CHTR2AHTR2BMAPT
	SCHEMBL2014452	0.88	MAPT (0.45)	HTR6BRD4PGRHTR2CHTR2A
	SCHEMBL2014308	0.88	HTR6 (0.49)	HTR6PGRHTR2CHTR2BKDM4E
	SCHEMBL2018282	0.85	HTR2C (0.51)	HTR6BRD4PGRHTR2CHTR2A
	SCHEMBL2016961	0.84	PKM (0.52)	HTR6BRD4PGRHTR2CHTR2A
	SCHEMBL2015136	0.83	DDB1 (0.49)	HTR6BRD4HTR2CMAPTTRIM24
	SCHEMBL2017184	0.83	BRD4 (0.45)	HTR6BRD4HTR2CHTR2AHTR2B
	SCHEMBL2017386	0.83	HTR2C (0.47)	HTR6HTR2CHTR2AHTR2BMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.