SCHEMBL2015136

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2018282	0.89	HTR2C (0.51)	HTR6HTR2CBRD4LMNACASP3
	SCHEMBL2014308	0.86	HTR6 (0.49)	HTR6HTR2CLMNA
	SCHEMBL2015259	0.85	HTR6 (0.45)	DDB1CRBNHTR6HTR2CBRD4
	SCHEMBL2014452	0.85	MAPT (0.45)	DDB1CRBNHTR6HTR2CBRD4
	SCHEMBL692281	0.85	HTR6 (0.49)	HTR6HTR2CHDAC8HDAC1MAPT
	SCHEMBL2014952	0.84	DDB1 (0.49)	DDB1CRBNHTR6HTR2CBRD4
	SCHEMBL2017384	0.83	HTR6 (0.47)	HTR6HTR2CBRD4MAPTTRIM24
	SCHEMBL2016961	0.83	PKM (0.52)	PKLRDRD3HTR6HTR2CBRD4
	SCHEMBL2015014	0.82	SMN1; SMN2 (0.52)	HTR6HTR2CBRD4LMNAMAPT
	SCHEMBL2017668	0.81	BRD4 (0.48)	HTR6HTR2CBRD4LMNACASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.