SCHEMBL2018351

SCHEMBL2018351

CCCCCCCCCCCCCCCCCCOC1CC(COc2ccc(CO)c(OC)c2)CC(OCCCCCCCCCCCCCCCCCC)C1OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 5/20 0.46
CNR1 P21554 2/20 0.46
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
KMT2A Q03164 1/20 0.36
PARP15 Q460N3 1/20 0.36
PARP10 Q53GL7 1/20 0.36
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31193361 1.00 CNR2 (0.46) CNR2CNR1THRATHRBMEN1
SCHEMBL31193427 0.92 CNR1 (0.46) CNR2CNR1THRATHRBMEN1
SCHEMBL2019737 0.92 CNR1 (0.46) CNR2CNR1THRATHRBMEN1
SCHEMBL13505329 0.85 CNR1 (0.39) CNR2CNR1THRATHRBMEN1
SCHEMBL2018327 0.82 MAOB (0.45) CNR2CNR1THRATHRBALDH1A1
SCHEMBL13837524 0.81 CNR1 (0.43) CNR2CNR1THRATHRBMEN1
SCHEMBL2016511 0.81 NPC1 (0.42) MEN1ALDH1A1KMT2A
SCHEMBL2020613 0.80 S1PR2 (0.37)
SCHEMBL533740 0.77 MMP9 (0.38) ALDH1A1TSHR
SCHEMBL2018804 0.76 ALDH1A1 (0.43) CNR2CNR1THRATHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9353147-B2 Method for producing peptide AJINOMOTO CO., INC. (JP) 2016-05-31 US claimed
US-9353148-B2 Method for producing peptide AJINOMOTO CO., INC. (JP) 2016-05-31 US claimed
US-8859732-B2 Benzylic compound AJINOMOTO CO., INC. (JP) 2014-10-14 US claimed
US-20140088291-A1 METHOD FOR PRODUCING PEPTIDE AJINOMOTO CO., INC. (JP) 2014-03-27 US claimed
US-20140080999-A1 METHOD FOR PRODUCING PEPTIDE AJINOMOTO CO., INC. (JP) 2014-03-20 US claimed
EP-2518041-A1 BENZYL COMPOUND Ajinomoto Co., Inc. (JP) 2012-10-31 EP claimed
US-20110160433-A1 BENZYLIC COMPOUND AJINOMOTO CO., INC. (JP) 2011-06-30 US claimed
US-12351601-B2 Method for producing peptide continuously AJINOMOTO CO., INC. (JP) 2025-07-08 US disclosed
US-20250188118-A1 LIQUID PHASE PEPTIDE SYNTHESIS METHODS AMGEN INC. (US) 2025-06-12 US disclosed
US-11939404-B2 Method for producing cyclized peptide having intramolecular S-S bond AJINOMOTO CO., INC. (JP) 2024-03-26 US disclosed
US-20220041648-A1 METHOD FOR PRODUCING PEPTIDE CONTINUOUSLY AJINOMOTO CO., INC. (JP) 2022-02-10 US disclosed
EP-3882255-A1 METHOD FOR PRODUCING CYCLIZED PEPTIDE HAVING INTRAMOLECULAR S-S BOND AJINOMOTO CO., INC. (JP) 2021-09-22 EP disclosed
US-20210277063-A1 METHOD FOR PRODUCING CYCLIZED PEPTIDE HAVING INTRAMOLECULAR S-S BOND AJINOMOTO CO., INC. (JP) 2021-09-09 US disclosed
US-8859732-B2 Benzylic compound AJINOMOTO CO., INC. (JP) 2014-10-14 US disclosed
US-20140296483-A1 METHOD FOR REMOVING FMOC GROUP AJINOMOTO CO., INC. (JP) 2014-10-02 US disclosed
US-20140088291-A1 METHOD FOR PRODUCING PEPTIDE AJINOMOTO CO., INC. (JP) 2014-03-27 US disclosed
US-20140080999-A1 METHOD FOR PRODUCING PEPTIDE AJINOMOTO CO., INC. (JP) 2014-03-20 US disclosed
EP-2518041-A1 BENZYL COMPOUND Ajinomoto Co., Inc. (JP) 2012-10-31 EP disclosed
US-20110160433-A1 BENZYLIC COMPOUND AJINOMOTO CO., INC. (JP) 2011-06-30 US disclosed
US-20110160433-A1 BENZYLIC COMPOUND AJINOMOTO CO., INC. (JP) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250188118-A1 LIQUID PHASE PEPTIDE SYNTHESIS METHODS VIP, RNGTT, SSU72 CNR2 4682/4885CNR1 4670/4885THRA 2680/4885
US-20220041648-A1 METHOD FOR PRODUCING PEPTIDE CONTINUOUSLY VIP, NPPA, NGLY1 CNR2 4197/4885CNR1 4108/4885THRA 2016/4885
US-20110160433-A1 BENZYLIC COMPOUND VIP, NGLY1, FURIN CNR2 2139/4885CNR1 2142/4885THRA 3778/4885
US-11939404-B2 Method for producing cyclized peptide having intramolecular S-S bond SPPL2B, PTMS, VIP CNR2 4671/4885CNR1 4502/4885THRA 1246/4885
US-20140080999-A1 METHOD FOR PRODUCING PEPTIDE VIP, ANPEP, NPPA CNR2 4329/4885CNR1 4353/4885THRA 3003/4885
US-20140296483-A1 METHOD FOR REMOVING FMOC GROUP ESD, HM13, FURIN CNR2 2710/4885CNR1 3237/4885THRA 3109/4885
US-20140088291-A1 METHOD FOR PRODUCING PEPTIDE ANPEP, NPPA, LNPEP CNR2 4129/4885CNR1 3645/4885THRA 2857/4885
US-12351601-B2 Method for producing peptide continuously VIP, NPPA, NGLY1 CNR2 4197/4885CNR1 4108/4885THRA 2016/4885
US-20210277063-A1 METHOD FOR PRODUCING CYCLIZED PEPTIDE HAVING INTRAMOLECULAR S-S BOND SPPL2B, PTMS, VIP CNR2 4671/4885CNR1 4502/4885THRA 1246/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.