Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909909 | 0.84 | LMNA (0.37) | ALDH1A1MAPTGAAMAPK1SCN5A | |
| SCHEMBL20845190 | 0.83 | TP53 (0.35) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL19909972 | 0.82 | NPC1 (0.32) | ALDH1A1MAPTGAAKDM4ELMNA | |
| SCHEMBL20686632 | 0.81 | GABRA1 (0.34) | ALOX15TSHRCYP2C19HIF1ATDP1 | |
| SCHEMBL22038786 | 0.81 | CTSD (0.43) | HIF1AALDH1A1MAPTKDM4ELMNA | |
| SCHEMBL23506160 | 0.80 | ALDH1A1 (0.33) | TDP1ALDH1A1MAPTGAA | |
| SCHEMBL22037196 | 0.79 | HTR7 (0.38) | — | |
| SCHEMBL20342686 | 0.78 | P2RX7 (0.35) | TDP1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL20195510 | 0.77 | MAPK8 (0.33) | — | |
| SCHEMBL21317950 | 0.77 | NOTUM (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |