SCHEMBL2019741

SCHEMBL2019741

CO[Si](C)(CN=C=S)OC

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.33
MIF P14174 2/20 0.32
NAAA Q02083 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2022853 0.77 MIF (0.38) TRPA1MIFNAAA
SCHEMBL139291 0.75
SCHEMBL6446621 0.73
SCHEMBL551245 0.73 TRPA1 (0.47) TRPA1MIFNAAA
SCHEMBL17868114 0.73
SCHEMBL450056 0.65 ALDH1A1 (0.30)
SCHEMBL3835197 0.65 NAAA (0.44) TRPA1MIFNAAA
SCHEMBL10856138 0.61
SCHEMBL550615 0.61 NAAA (0.45) TRPA1MIFNAAA
SCHEMBL841893 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9284447-B2 Silane/urea compound as a heat-activated curing agent for epoxide resin compositions SIKA TECHNOLOGY AG (CH) 2016-03-15 US disclosed
US-20140216655-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATED CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2014-08-07 US disclosed
US-8728271-B2 Silane/urea compound as a heat-activatable curing agent for epoxide resin compositions SIKA TECHNOLOGY AG (CH) 2014-05-20 US disclosed
US-20110155320-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110155320-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SEM1, UBA1, UBA3 TRPA1 2333/4885MIF 3452/4885NAAA 781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.