SCHEMBL2022853

SCHEMBL2022853

CO[Si](CN=C=S)(OC)OC

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.38
TRPA1 O75762 4/20 0.35
NAAA Q02083 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2019741 0.77 TRPA1 (0.33) MIFTRPA1NAAA
SCHEMBL114874 0.74
SCHEMBL19182915 0.72
SCHEMBL550615 0.72 NAAA (0.45) MIFTRPA1NAAAALDH1A1
SCHEMBL2772741 0.71 TRPA1 (0.39) MIFTRPA1NAAAALDH1A1
SCHEMBL3835195 0.70 NAAA (0.48) MIFTRPA1NAAAALDH1A1
SCHEMBL17868114 0.69
SCHEMBL28819833 0.68 NAAA (0.32) NAAA
SCHEMBL4905526 0.67
SCHEMBL450056 0.61 ALDH1A1 (0.30) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524714-B As the silane compound/carbamide compound of the heat-activatable solidifying agent for composition epoxy resin SIKA TECHNOLOGY AG (CH) 2016-04-06 CN disclosed
US-8728271-B2 Silane/urea compound as a heat-activatable curing agent for epoxide resin compositions SIKA TECHNOLOGY AG (CH) 2014-05-20 US disclosed
CN-102131817-B Silane/urea compounds as heat-activatable curing agents for epoxy resin compositions SIKA TECHNOLOGY AG 2014-05-07 CN disclosed
CN-103524714-A Silane/urea compound as heat-activatable curing agent for epoxide resin compositions SIKA TECHNOLOGY AG 2014-01-22 CN disclosed
CN-102131817-A Silane/urea compounds as heat-activatable curing agents for epoxy resin compositions SIKA TECHNOLOGY AG 2011-07-20 CN disclosed
US-20110155320-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2011-06-30 US disclosed
EP-2161274-B1 Silane/urea compound as heat-activated hardener for epoxy resin compounds SIKA TECHNOLOGY AG (CH) 2010-05-19 EP disclosed
EP-2161274-A1 Silane/urea compound as heat-activated hardener for epoxy resin compounds Sika Technology AG (CH) 2010-03-10 EP disclosed
WO-2010023234-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2010-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110155320-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SEM1, UBA1, UBA3 MIF 3452/4885TRPA1 2333/4885NAAA 781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.