Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21325263 | 0.80 | PARP15 (0.36) | PARP15PARP10HCAR2GPR84LMNA | |
| SCHEMBL20204753 | 0.74 | HMBS (0.37) | PARP15PARP10HCAR2BRD4SLC6A2 | |
| SCHEMBL24823620 | 0.70 | CA1 (0.43) | GPR84LMNAKDM4ESMN1; SMN2GRIN1 | |
| SCHEMBL16727170 | 0.69 | LMNA (0.47) | PARP15PARP10LMNAMAOASLC6A2 | |
| SCHEMBL14943724 | 0.67 | HTR1A (0.42) | PARP15PARP10KDM4EMEN1ALDH1A1 | |
| SCHEMBL20201747 | 0.67 | HCAR2 (0.35) | PARP15PARP10HCAR2BRD4CREBBP | |
| SCHEMBL20204751 | 0.65 | PARP15 (0.42) | PARP15PARP10BRD4SLC6A2CREBBP | |
| SCHEMBL19583295 | 0.63 | YTHDF2 (0.59) | LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL18122046 | 0.63 | ACACB (0.41) | PARP15PARP10GRIN1GRIN2B | |
| SCHEMBL20204815 | 0.63 | HTR1A (0.47) | LMNAKDM4EMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098208-A1 | NITROGEN RING LINKED DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |