Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368225 | 0.86 | ALDH1A1 (0.47) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL6372349 | 0.84 | L3MBTL1 (0.46) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL11131636 | 0.84 | MEN1 (0.71) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL6366932 | 0.83 | MAPT (0.45) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL2328263 | 0.78 | MEN1 (0.68) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL11225143 | 0.78 | ALDH1A1 (0.67) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL8159209 | 0.77 | MEN1 (0.66) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL7129845 | 0.77 | L3MBTL1 (0.53) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL11312705 | 0.77 | MEN1 (0.66) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 | |
| SCHEMBL10697720 | 0.76 | PABPC1 (0.64) | L3MBTL1ALDH1A1MAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005259-B2 | Packaging device for a hair dyeing product | L'OREAL (FR) | 2018-06-26 | — | — | US | disclosed |
| US-9125815-B2 | Agent for dyeing and/or bleaching keratinous fibres in two or more parts, comprising an alkaline composition in an inverse emulsion | L'OREAL (FR) | 2015-09-08 | — | — | US | disclosed |
| US-20130189206-A1 | AGENT FOR DYEING AND/OR BLEACHING KERATINOUS FIBRES IN TWO OR MORE PARTS, COMPRISING AN ALKALINE COMPOSITION IN AN INVERSE EMULSION | L'OREAL (FR) | 2013-07-25 | — | — | US | disclosed |
| WO-2011076790-A2 | METHOD FOR DYEING OR LIGHTENING KERATINOUS FIBRES IN THE PRESENCE OF VOLATILE LINEAR ALKANE(S) AND DEVICE. | L'OREAL (FR) | 2011-06-30 | — | — | WO | disclosed |
| US-7077873-B2 | Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye | L'Oréal, SA (FR) | 2006-07-18 | — | — | US | disclosed |
| US-7018428-B2 | Process for the preparation of a dyeing composition for the dyeing of keratinous fibers from pressurized steam | L'OREAL (FR) | 2006-03-28 | — | — | US | disclosed |
| US-20040255400-A1 | Process for the preparation of a dyeing composition for the dyeing of keratinous fibers from pressurized steam | L'OREAL S.A. (FR) | 2004-12-23 | — | — | US | disclosed |
| US-20040127692-A1 | Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye | L'OREAL S.A. (FR) | 2004-07-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127692-A1 | Composition for the dyeing of human keratinous fibres comprising a monocationic monoazo dye | KRT18, WNT3, DSG1 | L3MBTL1 4629/4885ALDH1A1 2440/4885MAPK1 2305/4885 |
| US-20040255400-A1 | Process for the preparation of a dyeing composition for the dyeing of keratinous fibers from pressurized steam | KRT18, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, PKM | L3MBTL1 4764/4885ALDH1A1 2714/4885MAPK1 2282/4885 |
| US-20130189206-A1 | AGENT FOR DYEING AND/OR BLEACHING KERATINOUS FIBRES IN TWO OR MORE PARTS, COMPRISING AN ALKALINE COMPOSITION IN AN INVERSE EMULSION | KRT18, LIPA, HBB | L3MBTL1 2727/4885ALDH1A1 1082/4885MAPK1 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.