Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 5/20 | 0.44 |
| ▸ | CTSA | P10619 | 11/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217174 | 0.89 | GRN (0.43) | CTSA | |
| SCHEMBL20217148 | 0.89 | GRN (0.43) | CTSA | |
| SCHEMBL20217147 | 0.87 | CTSA (0.40) | KCNK3CTSA | |
| SCHEMBL20217493 | 0.86 | CTSA (0.39) | CTSA | |
| SCHEMBL20217243 | 0.84 | KDM4E (0.51) | PPARG | |
| SCHEMBL20217242 | 0.79 | AKT1 (0.41) | — | |
| SCHEMBL20217596 | 0.78 | KCNK3 (0.40) | KCNK3 | |
| SCHEMBL20217342 | 0.78 | APLNR (0.49) | PPARG | |
| SCHEMBL20217176 | 0.77 | ROCK2 (0.50) | — | |
| SCHEMBL20217347 | 0.76 | ALDH1A1 (0.47) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |