Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 11/20 | 0.50 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.48 |
| ▸ | TACR3 | P29371 | 3/20 | 0.45 |
| ▸ | TACR2 | P21452 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217342 | 0.91 | APLNR (0.49) | PPARGTACR3 | |
| SCHEMBL20217347 | 0.88 | ALDH1A1 (0.47) | KDM4EALDH1A1LMNAPPARG | |
| SCHEMBL20217138 | 0.88 | ROCK1 (0.52) | KDM4ETACR3 | |
| SCHEMBL20217203 | 0.87 | TAS1R3 (0.59) | TACR3 | |
| SCHEMBL20217176 | 0.87 | ROCK2 (0.50) | LMNA | |
| SCHEMBL20217320 | 0.84 | KCNK3 (0.44) | PPARG | |
| SCHEMBL20217596 | 0.82 | KCNK3 (0.40) | ALDH1A1LMNAHPGD | |
| SCHEMBL2473197 | 0.78 | KDM4E (0.71) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL4797426 | 0.78 | KDM4E (0.71) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL20217634 | 0.77 | TAS1R3 (0.40) | KDM4EALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |