Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 16/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217138 | 0.91 | ROCK1 (0.52) | APLNRTACR3 | |
| SCHEMBL20217243 | 0.91 | KDM4E (0.51) | TACR3PPARG | |
| SCHEMBL20217347 | 0.86 | ALDH1A1 (0.47) | PPARG | |
| SCHEMBL20217203 | 0.85 | TAS1R3 (0.59) | APLNRTACR3 | |
| SCHEMBL20217534 | 0.78 | ROCK1 (0.48) | APLNRTACR3PPARG | |
| SCHEMBL20217176 | 0.78 | ROCK2 (0.50) | — | |
| SCHEMBL20217320 | 0.78 | KCNK3 (0.44) | PPARG | |
| SCHEMBL6607705 | 0.77 | UTS2R (0.58) | TACR3 | |
| SCHEMBL29995987 | 0.77 | APLNR (0.63) | APLNRTACR3PPARG | |
| SCHEMBL20217596 | 0.76 | KCNK3 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |