Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217347 | 0.73 | ALDH1A1 (0.47) | TAS1R3TAS1R1LMNAALDH1A1PPARG | |
| SCHEMBL20217615 | 0.70 | CTSA (0.44) | TAS1R3TAS1R1LMNAROCK2ROCK1 | |
| SCHEMBL20217652 | 0.70 | TAS1R3 (0.40) | TAS1R3TAS1R1LMNAPPARG | |
| SCHEMBL20217226 | 0.69 | CYP3A4 (0.44) | TAS1R3TAS1R1ALDH1A1PPARGLNPEP | |
| SCHEMBL4173638 | 0.66 | TAS1R3 (0.76) | TAS1R3TAS1R1ALDH1A1MAPT | |
| SCHEMBL8040417 | 0.66 | PPARG (0.49) | LMNAALDH1A1PPARG | |
| SCHEMBL10318421 | 0.65 | ROCK1 (0.58) | TAS1R3TAS1R1ROCK2ROCK1 | |
| SCHEMBL2974674 | 0.65 | PPARG (0.51) | LMNAALDH1A1PPARG | |
| SCHEMBL4537762 | 0.65 | PPARG (0.48) | LMNAALDH1A1PPARGLNPEPMAPT | |
| SCHEMBL20217342 | 0.65 | APLNR (0.49) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |