Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20219381 | 0.84 | TLR8 (0.34) | ALDH1A1TLR8TLR7POLB | |
| SCHEMBL20219702 | 0.83 | ALDH1A1 (0.35) | ALDH1A1MEN1KMT2ATLR8TLR7 | |
| SCHEMBL20219428 | 0.81 | TLR7 (0.40) | ALDH1A1TLR8TLR7 | |
| SCHEMBL23472603 | 0.81 | TLR8 (0.36) | ALDH1A1TLR8TLR7POLB | |
| SCHEMBL23472521 | 0.80 | FLT3 (0.34) | ALDH1A1TLR8TLR7POLB | |
| SCHEMBL23472434 | 0.78 | CYP2D6 (0.40) | ALDH1A1TLR8TLR7 | |
| SCHEMBL20219386 | 0.77 | SCN9A (0.36) | ALDH1A1TLR8TLR7POLB | |
| SCHEMBL23472511 | 0.76 | CHRNB2 (0.43) | KMT2ATLR8TLR7 | |
| SCHEMBL20219322 | 0.76 | CYP1A2 (0.42) | ALDH1A1MEN1KMT2ATLR8TLR7 | |
| SCHEMBL15470345 | 0.76 | L3MBTL1 (0.46) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3330257-A1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | Janssen Sciences Ireland UC (IE) | 2018-06-06 | — | — | EP | disclosed |