Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23472434 | 0.88 | CYP2D6 (0.40) | TLR7TLR8CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL20219324 | 0.85 | CHRNB2 (0.47) | CHRNB2CHRNA4TLR7TLR8CYP3A4 | |
| SCHEMBL15470053 | 0.84 | TLR7 (0.53) | CHRNB2CHRNA4TLR7TLR8CYP3A4 | |
| SCHEMBL20219444 | 0.81 | TLR7 (0.42) | TLR7TLR8CYP3A4CYP1A2TYRO3 | |
| SCHEMBL23472425 | 0.80 | CASP6 (0.41) | TLR7TLR8CYP3A4CYP1A2GBA1 | |
| SCHEMBL20219322 | 0.79 | CYP1A2 (0.42) | TLR7TLR8CYP3A4CYP1A2GBA1 | |
| SCHEMBL20219428 | 0.78 | TLR7 (0.40) | TLR7TLR8CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL20219702 | 0.78 | ALDH1A1 (0.35) | TLR7TLR8KMT2A | |
| SCHEMBL20219466 | 0.77 | TLR7 (0.42) | TLR7TLR8CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL23472658 | 0.77 | HTR1A (0.47) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590928-B1 | PYRIMIDINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN SCIENCES IRELAND UNLIMITED CO (IE) | 2021-06-09 | — | — | EP | disclosed |