SCHEMBL202252

SCHEMBL202252

CC(C)(c1ccc(N)cc1)c1ccc(Oc2ccc(C(=O)c3ccc(Oc4ccc(C(C)(C)c5ccc(N)cc5)cc4)cc3)cc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 5/20 0.58
▸ MAPT P10636 4/20 0.58
▸ RAB9A P51151 3/20 0.58
▸ HPGD P15428 3/20 0.58
▸ NPC1 O15118 2/20 0.58
▸ MAPK1 P28482 1/20 0.58
▸ PARP10 Q53GL7 3/20 0.56
▸ TSHR P16473 2/20 0.47
▸ TDP1 Q9NUW8 2/20 0.47
▸ CYP3A4 P08684 1/20 0.47
▸ ELANE P08246 3/20 0.46
▸ SRD5A2 P31213 2/20 0.46
▸ SMN1; SMN2 Q16637 2/20 0.44
▸ HTT P42858 1/20 0.44
▸ KMT2A Q03164 1/20 0.44
▸ PARP15 Q460N3 1/20 0.44
▸ PARP14 Q460N5 1/20 0.44
▸ PARP16 Q8N5Y8 1/20 0.44
▸ PARP11 Q9NR21 1/20 0.44
▸ PARP4 Q9UKK3 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26764175 1.00 ALDH1A1 (0.58) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL26840191 1.00 ALDH1A1 (0.58) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL28889574 1.00 ALDH1A1 (0.58) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL14354267 0.91 MAPT (0.49) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL8762167 0.89 SRD5A2 (0.52) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL7921656 0.89 ALDH1A1 (0.49) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL5071236 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL204685 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL49650 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9AHPGDNPC1
SCHEMBL2677985 0.86 ALDH1A1 (0.76) ALDH1A1MAPTRAB9AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 388 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240182645-A1 POLY(AMIC ACID) COMPOSITION, POLYIMIDE COMPOSITION, ADHESIVE, AND LAMINATE MITSUI CHEMICALS, INC. (JP) 2024-06-06 — — US claimed
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INST SCI & TECH (KR) 2018-03-08 — — US claimed
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2016-07-07 — — US claimed
EP-2940015-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT Korea Advanced Institute of Science and Technology (KR) 2015-11-04 — — EP claimed
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-02-12 — — US claimed
US-5459233-A High temperature engineering aromatic polyimides MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1995-10-17 — — US claimed
US-5288843-A Polymerizing 4,4'-bis(3-aminophenoxy)biphenyl, pyromellitic dianhydride and a different aromaticdiamine; engineering plastics; molding mateials; aerospace; heat resistance; melt processibility MITSUI TOATSU CHEMICALS, INC. (JP) 1994-02-22 — — US claimed
US-4937316-A Process for preparing polyimides AMDAHL CORPORATION (US) 1990-06-26 — — US claimed
JP-62010051-A — — None — — JP disclosed
JP-1313560-A — — None — — JP disclosed
JP-1161054-A — — None — — JP disclosed
EP-4401112-A1 SEMICONDUCTOR APPARATUS AND METHOD FOR MANUFACTURING SEMICONDUCTOR APPARATUS University of Tsukuba (JP) 2024-07-17 — — EP disclosed
US-20240227363-A1 LAMINATE OF INORGANIC SUBSTRATE AND HEAT-RESISTANT POLYMER FILM TOYOBO CO., LTD. (JP) 2024-07-11 — — US disclosed
US-20240227373-A1 MULTILAYER BODY OF INORGANIC SUBSTRATE AND TRANSPARENT HEAT-RESISTANT POLYMER FILM TOYOBO CO., LTD. (JP) 2024-07-11 — — US disclosed
JP-H01313560-A AROMATIC POLYETHER-IMIDE RESIN COMPOSITION MITSUI TOATSU CHEM INC 1989-12-19 — — JP disclosed
JP-H01161054-A AROMATIC POLYAMIDE-IMIDE RESIN COMPOSITION MITSUI TOATSU CHEM INC 1989-06-23 — — JP disclosed
EP-0297808-A1 Polyimide and high-temperature adhesive thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-01-04 — — EP disclosed
EP-0294144-A1 Polyimide resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-12-07 — — EP disclosed
EP-0231953-A2 Light-absorbing resins for display device, display devices using the resin and method of manufacturing the same KABUSHIKI KAISHA TOSHIBA (JP) 1987-08-12 — — EP disclosed
JP-S6210051-A NOVEL ETHERDIAMINE AND PRODUCTION THEREOF MITSUI TOATSU CHEM INC 1987-01-19 — — JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150045481-A1 Asymmetric Diamine Compounds Containing Two Functional Groups and Polymers Therefrom AOC1, INMT, PRMT6 ALDH1A1 1726/4885MAPT 1275/4885RAB9A 2973/4885
US-20180066110-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT RICTOR, SGTA, SLC43A1 ALDH1A1 1659/4885MAPT 524/4885RAB9A 1963/4885
US-20160194449-A1 NOVEL POLYAMIDEIMIDE HAVING LOW THERMAL EXPANSION COEFFICIENT SGTA, RICTOR, SLC43A1 ALDH1A1 1627/4885MAPT 394/4885RAB9A 1336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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