Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 known ✓ | P22748 | 3/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.35 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17595204 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL11331421 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL9082732 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL8713969 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL4300381 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL11161642 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL18114851 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| SCHEMBL8717562 | 1.00 | CA4 (0.38) | CA4FAHD1CA1MEN1LDHA | |
| Ammonia Solution, Strong SCHEMBL1888501 | 0.90 | — | — | |
| Bicarbonate SCHEMBL8726923 | 0.89 | CA4 (0.40) | CA4FAHD1CA1MEN1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076897-A1 | USE OF AMYLASE VARIANTS AT LOW TEMPERATURE | NOVOZYMES A/S (DK) | 2011-06-30 | — | — | WO | disclosed |
| US-6136772-A | PRODUCING ENZYME-CONTAINING STARCH GRANULES | NOVO NORDISK A/S | 2000-10-24 | — | — | US | disclosed |
| US-6117664-A | ENDOGLUCANASE VARIANT WITH ADJUSTED HYDROGEN BONDING; FOR SOIL REMOVING DETERGENTS; FOR FABRIC SOFTNERS; FOR BIOPOLISHING TEXTILES; FOR EFFICIENT DRANIAGE OF PAPER PULP; FOR DEINKING; FOR PLANT DEGRADATION; FOR POLLUTION CONTROL | NOVO NORDISK A/S (DK) | 2000-09-12 | — | — | US | disclosed |
| US-6114509-A | METALLOENDOPEPTIDASE CONJUGATED TO POLYMER; DETERGENTS, SOAPS | NOVO NORDISK A/S (DK) | 2000-09-05 | — | — | US | disclosed |
| US-6106828-A | REDUCED RESPIRATORY ALLERGENICITY; CONJUGATED TO POLYMER | NOVO NORDISK A/S (DK) | 2000-08-22 | — | — | US | disclosed |
| US-6093562-A | ALPHA-AMYLASE ENZYME VARIANTS OF INCREASED THERMOSTABILITY OR DECREASED ISOELECTRIC POINT, HAVING SPECIFIED SUBSTITUTIONS OR DELETIONS TO THE PARENT ALPHA-AMYLASE AMINO ACID SEQUENCE; IMPROVED WASHING/TEXTILE DESIZING PERFORMANCE | NOVO NORDISK A/S (DK) | 2000-07-25 | — | — | US | disclosed |
| US-6071735-A | ACTIVE AT ALKALINE PH; AMINO ACID SEQUENCE AT LEAST 70% HOMOLOGOUS TO SEQUENCE OBTAINED FROM ACREMONIUM SPECIES; FOR LAUNDRY DETERGENT, STONE-WASHING OF DENIM, IMPROVING DRAINAGE OF AQUEOUS SUSPENSION OF PAPER PULP, DEINKING RECYCLED PAPER | NOVO NORDISK A/S (DK) | 2000-06-06 | — | — | US | disclosed |
| US-6022724-A | α-amylase mutants | NOVO NORDISK A/S (DK) | 2000-02-08 | — | — | US | disclosed |
| US-6001639-A | Endoglucanases | NOVO NORDISK A/S (DK) | 1999-12-14 | — | — | US | disclosed |
| US-5989169-A | GENETIC ENGINEERING | NOVO NORDISK A/S (DK) | 1999-11-23 | — | — | US | disclosed |
| WO-1996040791-A1 | MODIFICATION OF POLYPEPTIDES | NOVO NORDISK A/S (DK) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996030502-A1 | ALKALINE LIPOLYTIC ENZYME | NOVO NORDISK A/S (DK) | 1996-10-03 | — | — | WO | disclosed |
| WO-1996024665-A1 | BACILLUS PROTEASES | NOVO NORDISK A/S (DK) | 1996-08-15 | — | — | WO | disclosed |
| WO-1996017929-A1 | POLYPEPTIDE WITH REDUCED ALLERGENICITY | NOVO NORDISK A/S (DK) | 1996-06-13 | — | — | WO | disclosed |
| WO-1996013578-A1 | ENZYMATIC DETERGENT COMPOSITION | NOVO NORDISK A/S (DK) | 1996-05-09 | — | — | WO | disclosed |
| WO-1996013579-A1 | NOVEL LIPOLYTIC ENZYME | NOVO NORDISK A/S (DK) | 1996-05-09 | — | — | WO | disclosed |
| WO-1996011262-A1 | AN ENZYME AND ENZYME PREPARATION WITH ENDOGLUCANASE ACTIVITY | NOVO NORDISK A/S (DK) | 1996-04-18 | — | — | WO | disclosed |
| WO-1996010079-A1 | ENHANCERS SUCH AS ACETOSYRINGONE | NOVO NORDISK A/S (DK) | 1996-04-04 | — | — | WO | disclosed |
| WO-1996006930-A1 | COPRINACEAE LACCASES | NOVO NORDISK A/S (DK) | 1996-03-07 | — | — | WO | disclosed |
| WO-1995033039-A1 | DYE-TRANSFER INHIBITORY PREPARATION, AND DETERGENT COMPOSITION COMPRISING SUCH A PREPARATION | NOVO NORDISK A/S (DK) | 1995-12-07 | — | — | WO | disclosed |