Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 6/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23133281 | 0.94 | REN (0.48) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL20257155 | 0.94 | REN (0.48) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL23613619 | 0.89 | CTSL (0.48) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL20257150 | 0.88 | CTSK (0.51) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL23613597 | 0.86 | REN (0.49) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL20257223 | 0.85 | REN (0.48) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL23133192 | 0.83 | CTSK (0.56) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL20257141 | 0.83 | CTSK (0.56) | RENCTSLCTSBCAPN1CTSK | |
| SCHEMBL30657489 | 0.82 | REN (0.53) | REN | |
| SCHEMBL2034855 | 0.81 | CAPN1 (0.48) | CTSLCTSBCAPN1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10976306-B2 | Protein degradation inducing tag and usage thereof | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20180164289-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | TOKYO UNIVERSITY OF SCIENCE FOUNDATION (JP) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10976306-B2 | Protein degradation inducing tag and usage thereof | SENP8, SENP6, SENP7 | REN 3248/4885CTSL 1364/4885CTSB 624/4885 |
| US-20180164289-A1 | PROTEIN DEGRADATION INDUCING TAG AND USAGE THEREOF | SENP8, SENP6, SENP7 | REN 3248/4885CTSL 1364/4885CTSB 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.