Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.43 |
| ▸ | IDH2 | P48735 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14476938 | 0.82 | KIF11 (0.39) | KIF11IDH2KMT2AMEN1MAPK1 | |
| SCHEMBL15714285 | 0.77 | KIF11 (0.50) | KIF11IDH2KMT2AMEN1MAPK1 | |
| SCHEMBL22791425 | 0.75 | GAA (0.37) | KDM4EMAPTGAAALDH1A1CYP2C19 | |
| SCHEMBL20860302 | 0.75 | ADRA2A (0.32) | TSHR | |
| SCHEMBL9226482 | 0.73 | MEN1 (0.47) | KIF11IDH2KMT2AMEN1MAPK1 | |
| SCHEMBL9226616 | 0.73 | TAS2R14 (0.50) | KIF11IDH2KMT2AMEN1MAPK1 | |
| SCHEMBL9285908 | 0.73 | CES2 (0.46) | KIF11IDH2KMT2AMEN1MAPK1 | |
| SCHEMBL22620411 | 0.72 | PDE2A (0.41) | KIF11KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL20860303 | 0.72 | SIGMAR1 (0.37) | KMT2AMEN1MAPK1ALOX15TSHR | |
| SCHEMBL30167000 | 0.72 | ALDH1A1 (0.46) | KIF11KMT2AMEN1MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |