SCHEMBL20304553

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29579603	0.84	CA2 (0.49)	ALPLCA12CA1CA2CA9
	SCHEMBL22532346	0.83	TRPV4 (0.38)	ALPLTRPV4APLNRSLC22A12KDM4E
	SCHEMBL18601131	0.82	ALPL (0.41)	ALPLTRPV4CA12CA1CA2
	SCHEMBL19040355	0.82	TRPV4 (0.40)	ALPLTRPV4APLNRCA12CA1
	SCHEMBL21802032	0.81	CA12 (0.40)	ALPLCA12CA1CA2CA9
	SCHEMBL18601178	0.80	PTGS2 (0.42)	L3MBTL1LMNAHTTKMT2APOLB
	SCHEMBL30989845	0.77	TRPV4 (0.56)	TRPV4APLNRSLC22A12
	SCHEMBL22531441	0.74	APLNR (0.38)	TRPV4APLNRL3MBTL1KMT2AAGBL2
	SCHEMBL24314192	0.72	TRPV4 (0.50)	ALPLTRPV4CA12CA1CA2
	SCHEMBL21713328	0.72	APLNR (0.43)	TRPV4APLNRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.