SCHEMBL203207

SCHEMBL203207

CC(C)=C(C(=O)O)c1ccccc1Oc1cc(Oc2c(F)cccc2F)ncn1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GCK P35557 6/20 0.38
CHRM4 P08173 3/20 0.38
FFAR4 Q5NUL3 1/20 0.37
KMT2A Q03164 1/20 0.36
KDR P35968 1/20 0.36
MAPK14 Q16539 1/20 0.36
TNNI3K Q59H18 1/20 0.36
MRGPRX4 Q96LA9 1/20 0.34
KDM4E B2RXH2 1/20 0.34
RAF1 P04049 1/20 0.34
CHRM2 P08172 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203516 0.93 RAF1 (0.39) GCKCHRM4FFAR4KMT2AKDM4E
SCHEMBL8602336 0.90 GCK (0.38) GCKCHRM4FFAR4KMT2AKDR
SCHEMBL203208 0.90 GCK (0.38) GCKCHRM4FFAR4KMT2AKDR
SCHEMBL8584982 0.86 GCK (0.45) GCKKMT2AKDR
SCHEMBL2849776 0.84 GCK (0.38) GCKCHRM4FFAR4KMT2AKDR
SCHEMBL203795 0.83 SMN1; SMN2 (0.44) KMT2AKDM4ERAF1
SCHEMBL203517 0.83 KDR (0.39) GCKCHRM4KMT2AKDRRAF1
SCHEMBL7758309 0.83 KDR (0.39) GCKCHRM4KMT2AKDRRAF1
SCHEMBL709625 0.82 ALDH1A1 (0.40) KMT2AKDRTNNI3KKDM4E
SCHEMBL202840 0.82 ALDH1A1 (0.36) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 US disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 US disclosed
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF MERIAL, INC. 2010-09-30 US disclosed
WO-1997006676-A1 MICROBICIDAL FORMULATIONS BAYER AKTIENGESELLSCHAFT (DE) 1997-02-27 WO disclosed
EP-0743819-A1 USE OF 1,3,2-BENZODITHIAZOL-1-OXIDES AS MICROBIOCIDES FOR PROTECTING TECHNICAL MATERIALS, AND CERTAIN 1,3,2-BENZODITHIAZOL-1-OXIDES BAYER AG (DE) 1996-11-27 EP disclosed
EP-0736075-A1 ANTI-FOULING AGENT BAYER AG (DE) 1996-10-09 EP disclosed
WO-1996025044-A1 S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION BAYER AKTIENGESELLSCHAFT (DE) 1996-08-22 WO disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
WO-1995026962-A1 THIAZOLYLPYRAZOLINONES AND THEIR USE FOR PROTECTING TECHNICAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1995-10-12 WO disclosed
WO-1995021526-A1 USE OF 1,3,2-BENZODITHIAZOL-1-OXIDES AS MICROBIOCIDES FOR PROTECTING TECHNICAL MATERIALS, AND CERTAIN 1,3,2-BENZODITHIAZOL-1-OXIDES BAYER AKTIENGESELLSCHAFT (DE) 1995-08-17 WO disclosed
WO-1995017478-A1 ANTI-FOULING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249194-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 GCK 3827/4885CHRM4 190/4885FFAR4 719/4885
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 GCK 1212/4885CHRM4 2108/4885FFAR4 1057/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 GCK 3827/4885CHRM4 190/4885FFAR4 719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.