Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAF1 | P04049 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203796 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL7633885 | 0.89 | SMN1; SMN2 (0.42) | SMN1; SMN2MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL203516 | 0.88 | RAF1 (0.39) | SMN1; SMN2MAPTLMNAHTTMEN1 | |
| SCHEMBL709625 | 0.86 | ALDH1A1 (0.40) | SMN1; SMN2MAPTLMNAALDH1A1NPC1 | |
| SCHEMBL202840 | 0.86 | ALDH1A1 (0.36) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL8522022 | 0.85 | L3MBTL1 (0.39) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL205371 | 0.83 | PIN1 (0.41) | SMN1; SMN2ALDH1A1NPC1RAB9AMAPK1 | |
| SCHEMBL203207 | 0.83 | GCK (0.38) | KMT2ARAF1KDM4E | |
| SCHEMBL248232 | 0.83 | MEN1 (0.36) | ALDH1A1NPC1RAB9ATSHRMEN1 | |
| SCHEMBL203423 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150144027-A1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME | KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) | 2015-05-28 | — | — | US | disclosed |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2013-12-05 | — | — | US | disclosed |
| US-8445519-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2013-05-21 | — | — | US | disclosed |
| US-8409627-B2 | Particulate wood preservative and method for producing the same | OSMOSE, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8088801-B2 | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof | MERIAL LIMITED (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | MERIAL, INC. | 2010-09-30 | — | — | US | disclosed |
| US-7659228-B2 | Synergistic insecticide mixtures | BAYER AKTIENGESELLSCHAFT (DE) | 2010-02-09 | — | — | US | disclosed |
| US-20090280185-A1 | Particulate wood preservative and method for producing the same | PHIBROWOOD, LLC (US) | 2009-11-12 | — | — | US | disclosed |
| EP-1651401-B1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME | PHIBROWOOD LLC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1651401-A2 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME | Phibro-Tech, Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005007368-A2 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME | PHIBRO-TECH, INC. (US) | 2005-01-27 | — | — | WO | disclosed |
| US-20050009883-A1 | Fipronil and chloropyridine or chlorothiazole derivatives as antagonists of nicotinic acetylcholine receptors; protection of industrial materials and plants. | UHR HERMANN (DE) | 2005-01-13 | — | — | US | disclosed |
| US-20040258768-A1 | An aqueous solution of injectable particles of sparingly soluble copper salts not easily leached, yet with sustained microbiocidal and insecticidal effectiveness; impregnation by injection | OSMOSE, INC | 2004-12-23 | — | — | US | disclosed |
| US-20030134857-A1 | Synergistic insecticide mixtures | UHR HERMANN (DE) | 2003-07-17 | — | — | US | disclosed |
| US-6197799-B1 | PLANT SAFENING AGENTS; PRESERVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-03-06 | — | — | US | disclosed |
| US-5622546-A | Mould-resistant emulsion paints | BAYER AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| WO-1997001547-A1 | BENZAZOLE DERIVATIVES WITH MICROBIOCIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| EP-0726710-A1 | STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION | BAYER AG (DE) | 1996-08-21 | — | — | EP | disclosed |
| WO-1995034204-A1 | BACTERICIDE THIADIAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995012315-A1 | STABILISATION OF IODINE COMPOUNDS USING INORGANIC SUPPORTING MATERIALS FOR USE IN MATERIAL PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | SMN1; SMN2 3774/4885MAPT 4885/4885LMNA 4191/4885 |
| US-20030134857-A1 | Synergistic insecticide mixtures | CHRM3, CHRNA5, CHRNA2 | SMN1; SMN2 2343/4885MAPT 3838/4885LMNA 4338/4885 |
| US-20050009883-A1 | Fipronil and chloropyridine or chlorothiazole derivatives as antagonists of nicotinic acetylcholine receptors; protection of industrial materials and plants. | CHRM3, CHRNA5, CHRNE | SMN1; SMN2 3871/4885MAPT 2011/4885LMNA 4724/4885 |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | SMN1; SMN2 3774/4885MAPT 4885/4885LMNA 4191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.