SCHEMBL203516

SCHEMBL203516

CC(C)=C(C(=O)O)c1ccccc1Oc1cc(Oc2ccccc2F)ncn1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
RAF1 P04049 2/20 0.39
MRGPRX1 Q96LB2 2/20 0.38
CHRM2 P08172 2/20 0.38
CHRM4 P08173 2/20 0.38
CHRM5 P08912 2/20 0.38
CHRM1 P11229 2/20 0.38
CHRM3 P20309 2/20 0.38
MAP4K4 O95819 1/20 0.38
KMT2A Q03164 2/20 0.38
MEN1 O00255 1/20 0.38
CXCL8 P10145 1/20 0.38
GCK P35557 1/20 0.38
MAPT P10636 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
KDM4E B2RXH2 1/20 0.37
MAPK8 P45983 1/20 0.36
LMNA P02545 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL203207 0.93 GCK (0.38) RAF1CHRM2CHRM4CHRM5CHRM1
SCHEMBL203517 0.89 KDR (0.39) RAF1MRGPRX1CHRM2CHRM4CHRM5
SCHEMBL7758309 0.89 KDR (0.39) RAF1MRGPRX1CHRM2CHRM4CHRM5
SCHEMBL203795 0.88 SMN1; SMN2 (0.44) RAF1MRGPRX1MAP4K4KMT2AMEN1
SCHEMBL709625 0.86 ALDH1A1 (0.40) KMT2AMEN1MAPTSMN1; SMN2KDM4E
SCHEMBL8522022 0.85 L3MBTL1 (0.39) KMT2AMEN1CXCL8MAPTSMN1; SMN2
SCHEMBL202840 0.83 ALDH1A1 (0.36) KMT2AMEN1MAPTSMN1; SMN2LMNA
SCHEMBL205371 0.83 PIN1 (0.41) MAP4K4SMN1; SMN2
SCHEMBL203423 0.83 SMN1; SMN2 (0.40) KMT2AMEN1SMN1; SMN2MAPK8LMNA
SCHEMBL248232 0.83 MEN1 (0.36) KMT2AMEN1MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12464971-B2 Sowing device and method for treating seeds during planting SYNGENTA CROP PROTECTION AG (CH) 2025-11-11 US disclosed
US-20250241304-A1 FUNGICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 US disclosed
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2021-11-30 US disclosed
US-20150144027-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) 2015-05-28 US disclosed
US-8871277-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2014-10-28 US disclosed
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF AVENTIS AGRICULTURE (FR) 2013-12-05 US disclosed
US-20130230575-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME OSMOSE, INC. (US) 2013-09-05 US disclosed
US-8445519-B2 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof AVENTIS AGRICULTURE (FR) 2013-05-21 US disclosed
US-8409627-B2 Particulate wood preservative and method for producing the same OSMOSE, INC. (US) 2013-04-02 US disclosed
US-8088801-B2 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof MERIAL LIMITED (US) 2012-01-03 US disclosed
US-20040258768-A1 An aqueous solution of injectable particles of sparingly soluble copper salts not easily leached, yet with sustained microbiocidal and insecticidal effectiveness; impregnation by injection OSMOSE, INC 2004-12-23 US disclosed
US-20030134857-A1 Synergistic insecticide mixtures UHR HERMANN (DE) 2003-07-17 US disclosed
US-6197799-B1 PLANT SAFENING AGENTS; PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 2001-03-06 US disclosed
EP-0736075-A1 ANTI-FOULING AGENT BAYER AG (DE) 1996-10-09 EP disclosed
EP-0705160-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AG (DE) 1996-04-10 EP disclosed
EP-0690894-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AG (DE) 1996-01-10 EP disclosed
WO-1995034204-A1 BACTERICIDE THIADIAZOLIDINONES BAYER AKTIENGESELLSCHAFT (DE) 1995-12-21 WO disclosed
WO-1995017478-A1 ANTI-FOULING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1995-06-29 WO disclosed
WO-1995000303-A1 FUNGICIDAL ACTIVE-SUBSTANCE COMBINATION BAYER AKTIENGESELLSCHAFT (DE) 1995-01-05 WO disclosed
WO-1994021734-A1 PAINTS CONTAINING n-ALKYL-N-AZOLS AS PRESERVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030134857-A1 Synergistic insecticide mixtures CHRM3, CHRNA5, CHRNA2 RAF1 2237/4885MRGPRX1 280/4885CHRM2 11/4885
US-11185074-B2 Microbiocidal quinoline (thio)carboxamide derivatives IFNG, TLR1, IDO1 RAF1 2661/4885MRGPRX1 1010/4885CHRM2 1556/4885
US-20250241304-A1 FUNGICIDAL COMPOUNDS CYP1B1, CYP51A1, CYP1A1 RAF1 2132/4885MRGPRX1 1514/4885CHRM2 627/4885
US-20130324457-A1 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF CBR3, CBR1, NR5A2 RAF1 1486/4885MRGPRX1 185/4885CHRM2 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.