Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL203424 | 0.91 | HTR2C (0.41) | SMN1; SMN2LMNAHTR2CPOLBCCR2 | |
| SCHEMBL7625439 | 0.91 | HTR2C (0.41) | SMN1; SMN2LMNAHTR2CPOLBCCR2 | |
| SCHEMBL709625 | 0.87 | ALDH1A1 (0.40) | SMN1; SMN2LMNACCR2CYP1A2CYP2C9 | |
| SCHEMBL2854208 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2LMNAHTR2CPOLBCCR2 | |
| SCHEMBL203795 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL203516 | 0.83 | RAF1 (0.39) | SMN1; SMN2LMNAMEN1KMT2AMAPK8 | |
| SCHEMBL8522022 | 0.81 | L3MBTL1 (0.39) | SMN1; SMN2LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL2854206 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAHTR2CPOLBCCR2 | |
| SCHEMBL2854211 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2LMNAHTR2CPOLBCCR2 | |
| SCHEMBL202840 | 0.80 | ALDH1A1 (0.36) | SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11185074-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-11-30 | — | — | US | disclosed |
| US-20150144027-A1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING THE SAME | KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC.) | 2015-05-28 | — | — | US | disclosed |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | AVENTIS AGRICULTURE (FR) | 2013-12-05 | — | — | US | disclosed |
| US-8445519-B2 | 1-aryl-5-alkyl pyrazole derivative compounds, processes of making and methods of using thereof | AVENTIS AGRICULTURE (FR) | 2013-05-21 | — | — | US | disclosed |
| US-8409627-B2 | Particulate wood preservative and method for producing the same | OSMOSE, INC. (US) | 2013-04-02 | — | — | US | disclosed |
| US-8088801-B2 | Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof | MERIAL LIMITED (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | MERIAL, INC. | 2010-09-30 | — | — | US | disclosed |
| US-7659228-B2 | Synergistic insecticide mixtures | BAYER AKTIENGESELLSCHAFT (DE) | 2010-02-09 | — | — | US | disclosed |
| EP-1651401-B1 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME | PHIBROWOOD LLC (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1651401-A2 | PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME | Phibro-Tech, Inc. (US) | 2006-05-03 | — | — | EP | disclosed |
| WO-1997001547-A1 | BENZAZOLE DERIVATIVES WITH MICROBIOCIDAL PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-16 | — | — | WO | disclosed |
| WO-1996032235-A1 | TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1996-10-17 | — | — | WO | disclosed |
| WO-1996029314-A1 | THIOCARBAMOYL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-26 | — | — | WO | disclosed |
| EP-0730517-A1 | TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND | BAYER AG (DE) | 1996-09-11 | — | — | EP | disclosed |
| WO-1996025044-A1 | S-ARYL CYANIMIDOTHIO COMPOUNDS FOR MATERIAL PROTECTION | BAYER AKTIENGESELLSCHAFT (DE) | 1996-08-22 | — | — | WO | disclosed |
| WO-1996010915-A1 | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-18 | — | — | WO | disclosed |
| WO-1995034204-A1 | BACTERICIDE THIADIAZOLIDINONES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-21 | — | — | WO | disclosed |
| WO-1995026962-A1 | THIAZOLYLPYRAZOLINONES AND THEIR USE FOR PROTECTING TECHNICAL MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |
| WO-1995014558-A1 | TIMBER PRESERVATIVE CONTAINING A COPPER COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1995-06-01 | — | — | WO | disclosed |
| WO-1995011786-A1 | TIMBER PROTECTING MEDIUM CONTAINING A COPPER COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1995-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249194-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | SMN1; SMN2 3774/4885LMNA 4191/4885HTR2C 865/4885 |
| US-11185074-B2 | Microbiocidal quinoline (thio)carboxamide derivatives | IFNG, TLR1, IDO1 | SMN1; SMN2 4749/4885LMNA 4449/4885HTR2C 1200/4885 |
| US-20130324457-A1 | 1-ARYL-5-ALKYL PYRAZOLE DERIVATIVE COMPOUNDS, PROCESSES OF MAKING AND METHODS OF USING THEREOF | CBR3, CBR1, NR5A2 | SMN1; SMN2 3774/4885LMNA 4191/4885HTR2C 865/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.