SCHEMBL2036053

SCHEMBL2036053

C=C(C)C(=O)OCc1cc2ccccc2c2ccccc12

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
MAPT P10636 1/20 0.40
CYP1A2 P05177 2/20 0.38
KDM4E B2RXH2 2/20 0.36
HSD17B10 Q99714 2/20 0.36
FAAH O00519 1/20 0.36
TRPM4 Q8TD43 1/20 0.36
GPR84 Q9NQS5 1/20 0.35
MAPK1 P28482 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
RXFP1 Q9HBX9 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
TSHR P16473 1/20 0.34
GLA P06280 1/20 0.34
CYP2C19 P33261 1/20 0.34
ELANE P08246 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29503667 0.86 MEN1 (0.43) ALDH1A1HPGDMAPTMEN1KMT2A
SCHEMBL29625710 0.82 EPHX1 (0.49) ALDH1A1HPGDMAPTCYP1A2KDM4E
SCHEMBL216321 0.82 EPHX1 (0.49) ALDH1A1HPGDMAPTCYP1A2KDM4E
SCHEMBL1130685 0.82 KMT2A (0.50) MEN1KMT2AATM
SCHEMBL15356647 0.82 KMT2A (0.43) ALDH1A1HPGDMAPTCYP1A2KDM4E
SCHEMBL216103 0.81 MTNR1A (0.46) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL4352775 0.80 TSHR (0.37) ALDH1A1MAPTKDM4EMEN1KMT2A
SCHEMBL21864381 0.80 ALDH1A1 (0.50) ALDH1A1HPGDMAPTCYP1A2KDM4E
Ammonia Solution, Strong SCHEMBL29224022 0.80 MTNR1A (0.45) ALDH1A1KDM4ENPSR1MEN1KMT2A
SCHEMBL4349485 0.79 TACR1 (0.41) ALDH1A1HPGDMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808855-B1 Fluorescent polymers and coating compositions ROHM & HAAS (US) 2002-07-17 EP claimed
US-6344654-B1 AN ETHYLENICALLY UNSATURATED MONOMER IS COPOLYMERIZED WITH A POLYNUCLEAR AROMATIC HYDROCARBON OR A SUBSTITUTED AROMATIC DERIVATIVE THEREOF, SUCH THAT THE RESULTANT POLYMER IS FLUORESCENT. ROHM AND HAAS COMPANY 2002-02-05 US claimed
EP-0808855-A2 Fluorescent polymers and coating compositions ROHM AND HAAS COMPANY (US) 1997-11-26 EP claimed
US-11733609-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-08-22 US disclosed
US-11733609-B2 Silicon-containing underlayers ROHM AND HAAS ELECTRONIC MATERIALS LLC (US) 2023-08-22 US disclosed
US-20210397093-A1 SILICON-CONTAINING UNDERLAYERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2021-12-23 US disclosed
WO-2021131395-A1 ADHESIVE AGENT COMPOSITION, LAYERED BODY, METHOD FOR PRODUCING LAYERED BODY, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT 東京応化工業株式会社 2021-07-01 WO disclosed
EP-3004050-B1 CYANOSTILBENES ROLIC TECH AG (CH) 2020-09-02 EP disclosed
CN-110537126-A Optical waveguide formation composition comprising reactive silesquioxane compound NISSAN CHEMICAL CORP 2019-12-03 CN disclosed
US-10329486-B2 Cyanostilbenes ROLIC AG (CH) 2019-06-25 US disclosed
US-20190146343-A1 SILICON-CONTAINING UNDERLAYERS ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2019-05-16 US disclosed
US-20080274304-A1 Functionalized Photoreactive Compounds ROLIC AG (CH) 2008-11-06 US disclosed
JP-2007277581-A METHOD OF USING FLUORESCENT POLYMER IN COATING AND COATING COMPOSITION ROHM & HAAS CO 2007-10-25 JP disclosed
EP-1764405-A1 Functionalized photoreactive compounds Rolic AG (CH) 2007-03-21 EP disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 US disclosed
EP-0808855-B1 Fluorescent polymers and coating compositions ROHM & HAAS (US) 2002-07-17 EP disclosed
EP-1205500-A2 Method for identifying and quantifying fluorescent polymers ROHM AND HAAS COMPANY (US) 2002-05-15 EP disclosed
US-6344654-B1 AN ETHYLENICALLY UNSATURATED MONOMER IS COPOLYMERIZED WITH A POLYNUCLEAR AROMATIC HYDROCARBON OR A SUBSTITUTED AROMATIC DERIVATIVE THEREOF, SUCH THAT THE RESULTANT POLYMER IS FLUORESCENT. ROHM AND HAAS COMPANY 2002-02-05 US disclosed
US-5897811-A POLYMERIZING ONE OR MORE ETHYLENICALLY UNSATURATED MONOMERS WITH A FLUORESCENT COMPOUND SELECTED FROM NAPHTHALENE, ANTHRACENE, PHENANTHRENE FLUORANTHENE, PYRENE, CHRYSENE, TRIPHENYLENE, AND PERYLENE, AND THEIR DERIVATIVES ROHM AND HAAS COMPANY (US) 1999-04-27 US disclosed
EP-0808855-A2 Fluorescent polymers and coating compositions ROHM AND HAAS COMPANY (US) 1997-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080274304-A1 Functionalized Photoreactive Compounds PCNA, PIN1, MAP1LC3C ALDH1A1 147/4885HPGD 1529/4885MAPT 1166/4885
US-10329486-B2 Cyanostilbenes LATS1, LATS2, CRY1 ALDH1A1 2838/4885HPGD 4309/4885MAPT 930/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.