Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20373360 | 0.93 | MET (0.40) | POLBKDM4EALDH1A1MCHR1 | |
| SCHEMBL20373449 | 0.86 | SYK (0.38) | NOX4 | |
| SCHEMBL20373588 | 0.85 | BRD4 (0.37) | NOX4GRM4BRD4 | |
| SCHEMBL20373284 | 0.84 | KDM4E (0.36) | NOX4CNR2KDM4EALDH1A1MCHR1 | |
| SCHEMBL20373445 | 0.81 | TLR7 (0.33) | NOX4KDM4EALDH1A1BRD4 | |
| SCHEMBL20373452 | 0.81 | KCNA5 (0.40) | NOX4CNR2 | |
| SCHEMBL20373361 | 0.81 | AVPR2 (0.34) | NOX4POLBKDM4EALDH1A1MCHR1 | |
| SCHEMBL20373438 | 0.80 | LMNA (0.41) | CNR1CNR2KDM4EALDH1A1MAOB | |
| SCHEMBL20373754 | 0.80 | TLR7 (0.37) | NOX4KDM4EBRD4 | |
| SCHEMBL20373288 | 0.78 | S1PR3 (0.37) | NOX4KDM4EALDH1A1MCHR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3092227-B1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS BROMODOMAIN INHIBITORS | ORION CORP (FI) | 2018-07-11 | — | — | EP | disclosed |