Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.45 |
| ▸ | RARG | P13631 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 2/20 | 0.45 |
| ▸ | RARA | P10276 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 5/20 | 0.41 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044179 | 0.91 | TRPA1 (0.44) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL9953603 | 0.91 | TRPA1 (0.44) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL16606707 | 0.91 | TRPA1 (0.44) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL1636049 | 0.86 | TRPA1 (0.46) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL2033387 | 0.85 | TRPA1 (0.43) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL18084307 | 0.85 | TRPA1 (0.41) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL9202931 | 0.84 | RARB (0.41) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL13554953 | 0.83 | ALDH1A1 (0.41) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL9205369 | 0.82 | CYP1A2 (0.49) | RARBRARGRXRARARATRPA1 | |
| SCHEMBL9201572 | 0.82 | CYP1A2 (0.49) | RARBRARGRXRARARATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268346-B1 | PROCESSES FOR THE PREPARATION OF UNSATURATED MALONATES | INT FLAVORS & FRAGRANCES INC (US) | 2021-05-05 | — | — | EP | disclosed |
| CN-107428662-B | Process for the preparation of unsaturated malonic esters | 国际香料和香精公司 | 2021-04-23 | — | — | CN | disclosed |
| US-10081613-B2 | 2-(alkoxy or aryloxy carbonyl)-4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)hex-2-enoic acid compounds, its preparation and use | Givaudan, S.A. (CH) | 2018-09-25 | — | — | US | disclosed |
| EP-2513030-B2 | BETA-GAMMA UNSATURATED ESTERS AND PROCESS OF PRODUCTION OF BETA-GAMMA UNSATURATED ESTERS. | GIVAUDAN SA (CH) | 2018-08-29 | — | — | EP | disclosed |
| EP-2655325-B1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | GIVAUDAN SA (CH) | 2018-04-18 | — | — | EP | disclosed |
| EP-2655325-B1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | GIVAUDAN SA (CH) | 2018-04-18 | — | — | EP | disclosed |
| EP-1989170-B1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | FIRMENICH & CIE (CH) | 2018-04-11 | — | — | EP | disclosed |
| EP-3268346-A1 | PROCESSES FOR THE PREPARATION OF UNSATURATED MALONATES | International Flavors & Fragrances Inc. (US) | 2018-01-17 | — | — | EP | disclosed |
| US-20170305875-A1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1- ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | GIVAUDAN SA (CH) | 2017-10-26 | — | — | US | disclosed |
| US-20170305875-A1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1- ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | GIVAUDAN SA (CH) | 2017-10-26 | — | — | US | disclosed |
| US-8765980-B2 | Organic compounds | GIVAUDAN S.A. (CH) | 2014-07-01 | — | — | US | disclosed |
| EP-2655325-A1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | Givaudan SA (CH) | 2013-10-30 | — | — | EP | disclosed |
| US-20120271059-A1 | Organic Compounds | GIVAUDAN SA (CH) | 2012-10-25 | — | — | US | disclosed |
| EP-2513030-A1 | ORGANIC COMPOUNDS | Givaudan SA (CH) | 2012-10-24 | — | — | EP | disclosed |
| WO-2012085056-A1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | GIVAUDAN SA (CH) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012085056-A1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | GIVAUDAN SA (CH) | 2012-06-28 | — | — | WO | disclosed |
| WO-2011073387-A1 | ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2011-06-23 | — | — | WO | disclosed |
| US-20100168462-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | FIRMENICH SA (CH) | 2010-07-01 | — | — | US | disclosed |
| EP-1989170-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | Firmenich S.A. (CH) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007096791-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | FIRMENICH SA (CH) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305875-A1 | 2-(ALKOXY OR ARYLOXY CARBONYL)-4-METHYL-6-(2,6,6-TRIMETHYLCYCLOHEX-1- ENYL)HEX-2-ENOIC ACID COMPOUNDS, ITS PREPARATION AND USE | HRH2, HRH1, ENY2 | RARB 432/4885RARG 574/4885RXRA 195/4885 |
| US-20100168462-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | GNE, ECH1, ECI1 | RARB 592/4885RARG 567/4885RXRA 1347/4885 |
| US-20120271059-A1 | Organic Compounds | HSD17B12, HSD17B1, MAL2 | RARB 408/4885RARG 568/4885RXRA 1041/4885 |
| US-10081613-B2 | 2-(alkoxy or aryloxy carbonyl)-4-methyl-6-(2,6,6-trimethylcyclohex-1-enyl)hex-2-enoic acid compounds, its preparation and use | HRH2, HRH1, ENY2 | RARB 432/4885RARG 574/4885RXRA 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.