SCHEMBL20482157

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628757	0.86	ALDH1A1 (0.48)	ALDH1A1HPGDSMN1; SMN2HRH3ACACB
	SCHEMBL21656736	0.85	LMNA (0.47)	ALDH1A1HPGDSMN1; SMN2HRH3LMNA
	SCHEMBL21628603	0.85	SMN1; SMN2 (0.56)	ALDH1A1HPGDSMN1; SMN2NPC1RAB9A
	SCHEMBL4255729	0.85	RXRA (0.54)	HRH3ACACBACACALMNAOPRM1
	SCHEMBL20844518	0.85	HRH3 (0.50)	HPGDHRH3RAB9AACACBACACA
	SCHEMBL4252738	0.83	HRH3 (0.52)	HRH3ACACBACACALMNAOPRM1
	SCHEMBL21628519	0.83	NNMT (0.56)	ALDH1A1HRH3OPRM1OPRD1
	SCHEMBL21628824	0.82	HPGD (0.76)	ALDH1A1HPGDSMN1; SMN2NPC1RAB9A
	SCHEMBL21656686	0.82	LMNA (0.59)	ALDH1A1SMN1; SMN2HRH3ACACBACACA
	SCHEMBL21628611	0.81	ALDH1A1 (0.51)	ALDH1A1HPGDSMN1; SMN2HRH3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.