SCHEMBL21628757

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20482157	0.86	ALDH1A1 (0.51)	ALDH1A1HPGDSMN1; SMN2ACACBHRH3
	SCHEMBL21656515	0.86	MAPT (0.56)	ACACBHRH3ACACAHDAC8HDAC6
	SCHEMBL21656612	0.85	OPRM1 (0.56)	OPRM1OPRD1OPRK1
	SCHEMBL21628814	0.84	HPGD (0.69)	ALDH1A1HPGDSMN1; SMN2HDAC8HDAC6
	SCHEMBL21656683	0.84	LMNA (0.55)	ACACBACACAHDAC8HDAC6OPRM1
	SCHEMBL21628611	0.83	ALDH1A1 (0.51)	ALDH1A1HPGDSMN1; SMN2HRH3OPRM1
	SCHEMBL21657001	0.82	OPRM1 (0.55)	HPGDSMN1; SMN2ACACBHRH3ACACA
	SCHEMBL21656691	0.82	PDE4B (0.53)	ALDH1A1ACACBACACAHDAC8HDAC6
	SCHEMBL21628402	0.82	HDAC6 (0.61)	ACACBACACAHDAC8HDAC6OPRM1
	SCHEMBL21628603	0.81	SMN1; SMN2 (0.56)	ALDH1A1HPGDSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.