Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20482226 | 0.86 | HPGD (0.40) | ALDH1A1ADRB2HTTRAB9ASMN1; SMN2 | |
| SCHEMBL20482270 | 0.84 | RXRA (0.42) | PTPN1ALDH1A1ADRB2HTTHTR2C | |
| SCHEMBL20482885 | 0.83 | KMT2A (0.48) | ALDH1A1HTTRAB9ASMN1; SMN2MAPT | |
| SCHEMBL20482988 | 0.81 | HTR1A (0.40) | ALDH1A1HTTRAB9ASMN1; SMN2MAPT | |
| SCHEMBL20482653 | 0.78 | MAOA (0.45) | PTPN1ALDH1A1FFAR1FFAR4HTR2A | |
| SCHEMBL20482720 | 0.78 | FFAR1 (0.44) | PTPN1ALDH1A1FFAR1FFAR4HTR2A | |
| SCHEMBL20483084 | 0.75 | MAOA (0.44) | PTPN1ALDH1A1FFAR1FFAR4HTR2A | |
| SCHEMBL20482690 | 0.74 | ALDH1A1 (0.45) | PTPN1ALDH1A1FFAR1FFAR4ADRB2 | |
| SCHEMBL8070720 | 0.74 | ADRB2 (0.48) | ALDH1A1ADRB2HTTMEN1LMNA | |
| SCHEMBL20482556 | 0.73 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2MAPTATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018154466-A1 | DIHYDROQUINOLIZINONES AS ANTIVIRALS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-08-30 | — | — | WO | disclosed |