Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4558267 | 1.00 | NPSR1 (0.34) | NPSR1TSHRALDH1A1GAACYP3A4 | |
| SCHEMBL566225 | 0.73 | APEX1 (0.41) | SMN1; SMN2KDM4EHPGD | |
| SCHEMBL3975877 | 0.73 | PRSS1 (0.38) | — | |
| SCHEMBL10022876 | 0.72 | ALDH1A1 (0.33) | ALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL3976938 | 0.68 | FAAH (0.35) | — | |
| SCHEMBL568005 | 0.67 | PTPN1 (0.34) | — | |
| SCHEMBL5501498 | 0.67 | FAAH (0.31) | — | |
| SCHEMBL21837788 | 0.67 | USP2 (0.45) | NPSR1TSHRALDH1A1GAAPKM | |
| SCHEMBL21837790 | 0.67 | USP2 (0.45) | NPSR1TSHRALDH1A1GAAPKM | |
| SCHEMBL3257967 | 0.66 | ALDH1A1 (0.47) | NPSR1TSHRALDH1A1GAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090232874-A1 | FIBROUS MEMBRANE FOR BIOMEDICAL APPLICATION BASED ON POLY(ESTER-AMIDE)S | CORNELL UNIVERSITY (US) | 2009-09-17 | — | — | US | claimed |
| WO-2009102451-A1 | A FIBROUS MEMBRANE FOR BIOMEDICAL APPLICATION BASED ON POLY (ESTER-AMIDE)S | CORNELL UNIVERSITY (US) | 2009-08-20 | — | — | WO | claimed |
| US-8974815-B2 | Fibrous membrane for biomedical application based on poly(ester-amide)s | CORNELL UNIVERSITY (US) | 2015-03-10 | — | — | US | disclosed |
| US-8163269-B2 | Bioactive stents for type II diabetics and methods for use thereof | MEDIVAS, LLC | 2012-04-24 | — | — | US | disclosed |
| US-20110137406-A1 | BIOACTIVE STENTS FOR TYPE II DIABETICS AND METHODS FOR USE THEREOF | MEDIVAS, LLC (US) | 2011-06-09 | — | — | US | disclosed |
| US-7794706-B2 | Based on biodegradable polymers containing polyester amide (PEA), polyester urethane (PEUR), and polyester urea (PEU) and immunostimulatory adjuvants; for delivery of compositions that bind to major histocompatibility complexes (MHC) alleles | MEDIVAS, LLC (US) | 2010-09-14 | — | — | US | disclosed |
| US-20090232874-A1 | FIBROUS MEMBRANE FOR BIOMEDICAL APPLICATION BASED ON POLY(ESTER-AMIDE)S | CORNELL UNIVERSITY (US) | 2009-09-17 | — | — | US | disclosed |
| WO-2009102451-A1 | A FIBROUS MEMBRANE FOR BIOMEDICAL APPLICATION BASED ON POLY (ESTER-AMIDE)S | CORNELL UNIVERSITY (US) | 2009-08-20 | — | — | WO | disclosed |
| WO-2005112587-A3 | WOUND HEALING POLYMER COMPOSITIONS AND METHODS FOR USE THEREOF | MEDIVAS LLC (US) | 2009-04-09 | — | — | WO | disclosed |
| US-20080288057-A1 | Bioactive Stents For Type II Diabetics and Methods for Use Thereof | MEDIVAS, LLC | 2008-11-20 | — | — | US | disclosed |
| US-20080020015-A1 | Bioactive wound dressings and implantable devices and methods of use | MEDIVAS, LLC (US) | 2008-01-24 | — | — | US | disclosed |
| US-20050238689-A1 | Bioactive stents for type II diabetics and methods for use thereof | MEDIVAS, LLC (US) | 2005-10-27 | — | — | US | disclosed |
| WO-2005097186-A2 | BIOACTIVE STENTS FOR TYPE II DIABETICS AND METHODS FOR USE THEREOF | MEDIVAS, LLC (US) | 2005-10-20 | — | — | WO | disclosed |
| WO-2004075781-A2 | BIOACTIVE STENTS AND METHODS FOR USE THEREOF | MEDIVAS, LLC (US) | 2004-09-10 | — | — | WO | disclosed |
| US-20040170685-A1 | Bioactive stents and methods for use thereof | MEDIVAS, LLC (US) | 2004-09-02 | — | — | US | disclosed |
| EP-0898590-A1 | BIODEGRADABLE POLYMERS GRAFTED WITH AMINO ACIDS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1999-03-03 | — | — | EP | disclosed |
| WO-1997042249-A1 | BIODEGRADABLE POLYMERS GRAFTED WITH AMINO ACIDS | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-11-13 | — | — | WO | disclosed |
| US-5610241-A | Reactive graft polymer with biodegradable polymer backbone and method for preparing reactive biodegradable polymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 1997-03-11 | — | — | US | disclosed |
| US-5516881-A | Aminoxyl-containing radical spin labeling in polymers and copolymers | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| US-5485496-A | Gamma irradiation sterilizing of biomaterial medical devices or products, with improved degradation and mechanical properties | CORNELL RESEARCH FOUNDATION, INC. (US) | 1996-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080020015-A1 | Bioactive wound dressings and implantable devices and methods of use | MMP1, CXCL12, BMP2 | NPSR1 3205/4885TSHR 4865/4885ALDH1A1 1343/4885 |
| US-20050238689-A1 | Bioactive stents for type II diabetics and methods for use thereof | CD47, ITGB2, ITGA2 | NPSR1 326/4885TSHR 1794/4885ALDH1A1 3282/4885 |
| US-20090232874-A1 | FIBROUS MEMBRANE FOR BIOMEDICAL APPLICATION BASED ON POLY(ESTER-AMIDE)S | NAPA, FIBP, CUTA | NPSR1 2824/4885TSHR 4600/4885ALDH1A1 1037/4885 |
| US-20040170685-A1 | Bioactive stents and methods for use thereof | TGFB1, TGFB2, FGF2 | NPSR1 603/4885TSHR 4583/4885ALDH1A1 3586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.