Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20512229 | 0.88 | ALDH1A1 (0.53) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL20512258 | 0.83 | NPSR1 (0.51) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL20512264 | 0.82 | RAB9A (0.53) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL20512232 | 0.81 | ALDH1A1 (0.48) | CA12CA9MEN1KMT2AGAA | |
| SCHEMBL20512265 | 0.78 | ALDH1A1 (0.50) | CA12CA9MEN1KMT2AGAA | |
| SCHEMBL28529020 | 0.76 | MMP2 (0.54) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL20512274 | 0.75 | CYP19A1 (0.43) | CA12CYP1A2CYP3A4ATMCA9 | |
| SCHEMBL20512227 | 0.75 | ALDH1A1 (0.50) | CA12CA9L3MBTL1MEN1KMT2A | |
| SCHEMBL20512253 | 0.74 | ALDH1A1 (0.51) | L3MBTL1MEN1KMT2AMAPTGAA | |
| SCHEMBL20512270 | 0.74 | ALDH1A1 (0.55) | CA12CA9MEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-12-13 | — | — | US | disclosed |
| US-10138252-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-11-27 | — | — | US | disclosed |
| US-20180305371-A1 | NOVEL LACTONES | PURDUE RESEARCH FOUNDATION (US) | 2018-10-25 | — | — | US | disclosed |
| US-10087190-B1 | Lactones | PURDUE RESEARCH FOUNDATION (US) | 2018-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180354963-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | CA12 1994/4885CYP1A2 2159/4885CYP3A4 1074/4885 |
| US-20180305371-A1 | NOVEL LACTONES | DHPS, FDPS, LSS | CA12 1994/4885CYP1A2 2159/4885CYP3A4 1074/4885 |
| US-10138252-B1 | Lactones | DHPS, FDPS, LSS | CA12 1883/4885CYP1A2 1684/4885CYP3A4 763/4885 |
| US-10087190-B1 | Lactones | DHPS, FDPS, LSS | CA12 1883/4885CYP1A2 1684/4885CYP3A4 763/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.