SCHEMBL2051248

SCHEMBL2051248

CC(O)N(C(C)O)C(C)O.[MgH2]

nearest known ligand 0.42

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37338 0.95 ALDH1A1 (0.46) ALDH1A1LMNATDP1TSHR
SCHEMBL5595182 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
SCHEMBL7083879 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
Ammonia Solution, Strong SCHEMBL4280952 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
SCHEMBL1535125 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
Fluoride SCHEMBL923683 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
SCHEMBL3638600 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
Hydrochloric Acid SCHEMBL81805 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
SCHEMBL1267233 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR
Iodide SCHEMBL3898525 0.91 ALDH1A1 (0.42) ALDH1A1LMNATDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2642975-B1 SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME SHOWA DENKO KK (JP) 2016-08-24 EP disclosed
US-9180079-B2 Skin external preparation and method of producing same SHOWA DENKO K.K. (JP) 2015-11-10 US disclosed
US-20130287718-A1 SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME SHOWA DENKO K.K. (JP) 2013-10-31 US disclosed
EP-2642975-A2 SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME Showa Denko K.K. (JP) 2013-10-02 EP disclosed
WO-2012153825-A2 SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME SHOWA DENKO K.K. (JP) 2012-11-15 WO disclosed
EP-1381651-B1 POLYORGANOSILOXANE EMULSION COMPOSITION AND A COSMETIC MATERIAL MADE THEREFROM DOW CORNING TORAY CO LTD (JP) 2011-06-29 EP disclosed
US-20100322887-A1 HAIR NOURISHING COSMETIC SHOWA DENKO K.K. (JP) 2010-12-23 US disclosed
EP-2251002-A1 HAIR GROWING COSMETIC Showa Denko K.K. (JP) 2010-11-17 EP disclosed
US-20100280111-A1 SKIN EXTERNAL PREPARATIONS AND COSMETICS SHOWA DENKO K.K. (JP) 2010-11-04 US disclosed
US-20100273877-A1 EMULSIFIED SKIN EXTERNAL PREPARATIONS AND COSMETICS SHOWA DENKO K.K. (JP) 2010-10-28 US disclosed
EP-2238970-A1 EMULSION PREPARATION FOR EXTERNAL APPLICATION TO SKIN AND COSMETIC PREPARATION Showa Denko K.K. (JP) 2010-10-13 EP disclosed
EP-2238969-A1 PREPARATION FOR EXTERNAL APPLICATION TO SKIN AND COSMETIC PREPARATION Showa Denko K.K. (JP) 2010-10-13 EP disclosed
CN-101378747-A Whitening dermatological preparations SHOWA DENKO KK (JP) 2009-03-04 CN disclosed
EP-1858982-B1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING (US) 2008-08-27 EP disclosed
US-20080182833-A1 Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient DOW CORNING CORPORATION 2008-07-31 US disclosed
EP-1858982-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT Dow Corning Corporation (US) 2007-11-28 EP disclosed
US-7300648-B2 Polyorganosiloxane emulsion composition and a cosmetic material made therefrom DOWECORNING TORAY SILICONE, CO., LTD. (JP) 2007-11-27 US disclosed
WO-2006102010-A1 SILICONE EMULSION, METHOD OF PREPARING SAME, AND COSMETIC INGREDIENT DOW CORNING CORPORATION (US) 2006-09-28 WO disclosed
US-20040138373-A1 Polyorganosiloxane emulsion composition and a cosmetic material made therefrom DOW TORAY CO., LTD. (JP) 2004-07-15 US disclosed
US-4071487-A Anti-settling agents for pigmented aqueous lacquer and process for the manufacture of said agents HENKEL KGAA (DT) 1978-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100322887-A1 HAIR NOURISHING COSMETIC NDUFS6, NDUFA5, NDUFA11 ALDH1A1 220/4885LMNA 3967/4885TDP1 2188/4885
US-20100273877-A1 EMULSIFIED SKIN EXTERNAL PREPARATIONS AND COSMETICS CUTA, CRAT, SLC25A20 ALDH1A1 1631/4885LMNA 552/4885TDP1 3296/4885
US-20130287718-A1 SKIN EXTERNAL PREPARATION AND METHOD OF PRODUCING SAME RBP4, RBP1, PROC ALDH1A1 643/4885LMNA 472/4885TDP1 4222/4885
US-20080182833-A1 Silicone Emulsion, Method of Preparing Same, and Cosmetic Ingredient SQLE, CUTA, SMOX ALDH1A1 4578/4885LMNA 1060/4885TDP1 1122/4885
US-20100280111-A1 SKIN EXTERNAL PREPARATIONS AND COSMETICS H1-0, H1-2, CUTA ALDH1A1 1232/4885LMNA 440/4885TDP1 4098/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.