SCHEMBL20520573

SCHEMBL20520573

CC(C)(C)[S+]([O-])N=C(CCl)c1cnc(Cl)s1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20547933 1.00 LMNA (0.31) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL28411724 0.78 STK17B (0.35)
SCHEMBL20897909 0.77 ALDH1A1 (0.35)
SCHEMBL14824955 0.71
SCHEMBL567344 0.69 THRA (0.30)
SCHEMBL3439359 0.69 THRA (0.30)
SCHEMBL12264530 0.69 THRA (0.30)
SCHEMBL24387212 0.68 LMNA (0.31) LMNAPOLBRAB9AATML3MBTL1
SCHEMBL30639017 0.65
SCHEMBL30202482 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 US disclosed
US-20230159562-A1 PYRIMIDINIUM COMPOUNDS AND THEIR MIXTURES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2023-05-25 US disclosed
CN-116102580-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-12 CN disclosed
CN-116082366-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 CN disclosed
CN-116076518-A Pyrimidinium compounds and mixtures thereof for combating animal pests 巴斯夫欧洲公司 2023-05-09 CN disclosed
US-11578083-B2 Pyrimidinium compounds and their mixtures for combating animal pests BASF SE (DE) 2023-02-14 US disclosed
CN-110546153-B Process for preparing optically active 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds 巴斯夫欧洲公司 2022-09-06 CN disclosed
EP-3978504-A1 CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDINE DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2022-04-06 EP disclosed
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2021-12-02 US disclosed
EP-3601298-B1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2021-12-01 EP disclosed
US-11124528-B2 Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds BASF SE (DE) 2021-09-21 US disclosed
CN-111031798-A Method for controlling rice pests in rice 巴斯夫欧洲公司 2020-04-17 CN disclosed
WO-2020058010-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND BASF SE (DE) 2020-03-26 WO disclosed
EP-3615543-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2020-03-04 EP disclosed
US-20200055872-A1 Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds BASF SE (DE) 2020-02-20 US disclosed
EP-3601298-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2020-02-05 EP disclosed
CN-110546153-A process for preparing optically active 2, 3-dihydrothiazolo [3,2-A ] pyrimidin-4-ium compounds BASF SE 2019-12-06 CN disclosed
WO-2019043183-A1 METHOD OF CONTROLLING RICE PESTS IN RICE BASF SE (DE) 2019-03-07 WO disclosed
WO-2018197541-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-11-01 WO disclosed
WO-2018177970-A1 PROCESS FOR PREPARING CHIRAL 2,3-DIHYDROTHIAZOLO[3,2-A]PYRIMIDIN-4-IUM COMPOUNDS BASF SE (DE) 2018-10-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200055872-A1 Process for Preparing Optically Active 2,3-Dihydrothiazolo[3,2-A]pyrimidin-4-ium Compounds UMPS, UGP2, UGT1A4 LMNA 1582/4885POLB 807/4885RAB9A 1259/4885
US-20230159562-A1 PYRIMIDINIUM COMPOUNDS AND THEIR MIXTURES FOR COMBATING ANIMAL PESTS THOP1, NIT2, DDT LMNA 3730/4885POLB 1975/4885RAB9A 1817/4885
US-11578083-B2 Pyrimidinium compounds and their mixtures for combating animal pests THOP1, NIT2, DDT LMNA 3592/4885POLB 1824/4885RAB9A 1802/4885
US-11124528-B2 Process for preparing optically active 2,3-dihydrothiazolo[3,2-A]pyrimidin-4-ium compounds UMPS, UGP2, UGT1A4 LMNA 1582/4885POLB 807/4885RAB9A 1259/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 LMNA 2292/4885POLB 2186/4885RAB9A 1091/4885
US-20210368794-A1 PESTICIDAL MIXTURES COMPRISING A MESOIONIC COMPOUND ACHE, DDT, MTX2 LMNA 2292/4885POLB 2186/4885RAB9A 1091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.