Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CDK9 | P50750 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20523587 | 0.86 | HSD17B10 (0.46) | NR3C1ALDH1A1MCL1KEAP1NFE2L2 | |
| SCHEMBL20523469 | 0.83 | FYN (0.50) | SLC22A12MEN1KMT2APTK2ALOX5AP | |
| SCHEMBL20523546 | 0.80 | NR3C1 (0.41) | SLC22A12NR3C1PGRNR3C2AR | |
| SCHEMBL23747196 | 0.73 | NR3C1 (0.58) | SLC22A12NR3C1PGRNR3C2AR | |
| SCHEMBL29134896 | 0.72 | ACLY (0.54) | SLC22A12ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4860020 | 0.71 | PTGS1 (0.63) | SLC22A12NR3C1PGRNR3C2AR | |
| SCHEMBL26673643 | 0.71 | PTK2 (0.42) | SLC22A12ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13848266 | 0.71 | L3MBTL1 (0.54) | SLC22A12NR3C1PGRNR3C2AR | |
| SCHEMBL5637788 | 0.70 | KEAP1 (0.62) | SLC22A12NR3C1PGRNR3C2AR | |
| SCHEMBL20523657 | 0.70 | HPGD (0.51) | ALDH1A1MEN1KMT2AKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3600307-A1 | COMPOSITIONS FOR USE IN METHODS OF INHIBITING PROTEIN KINASES | University of Houston System (US) | 2020-02-05 | — | — | EP | disclosed |
| WO-2018183633-A1 | COMPOSITIONS FOR USE IN METHODS OF INHIBITING PROTEIN KINASES | UNIVERSITY OF HOUSTON SYSTEM (US) | 2018-10-04 | — | — | WO | disclosed |